Archive for the ‘Depression’ Category

Resilience and Succeeding In Life

Sunday, June 28th, 2009

Resilience is something that most people need to bounce back from whatever life throws at them. Everyone experiences difficulties in life, and some people will even experience traumatic events that create an upheaval in their lives. Resilience is the process by which people adapt to changes or crises, like death, divorce, tragedy, the loss of a job, or financial problems. Resilience is not a character trait - it can be learned by anyone, but learning resilience does require time and effort.

Several factors involved in resilience include having a loving support system, the ability to make plans and follow through with them, communication and problem-solving skills, having a positive view of yourself and your abilities, and the capability to manage your feelings and impulses. Building resilience is a different process for everyone, and what works for one person may not work for another. Each person should determine what works for them and do that.

It may be helpful to imagine resilience as a mountain climb to Mount Kinabalu for example. It is best to take that trip with someone else, particularly someone you love and trust. Having a plan in mind for how to navigate the trail is a good idea. Trusting your own instincts and abilities will help guide you along the way. Lastly, stopping along the trail to rest can be a great idea, but you will have to get back on and continue your journey in order to finish the trip.

Building resilience can be a challenging process. Here are a few tips for developing and strengthening resilience:

*Maintain good relationships with your family and friends, and accept their help in times of stress. Also, getting involved in community groups or faith-based organizations may help give you social support when you need it.

*Try to look at the big picture of life, and avoid viewing difficult times as insurmountable. Take small steps toward your goals and take one day at a time.

*Accept that change is a part of life and learn to embrace the circumstances that you cannot change.

*Keep working toward your goals every day, and ask yourself “What can I do today to move in the direction I need to go?”

*Keep a positive view of yourself and your ability to solve issues and challenges.

*Maintain a positive view of life and visualize what you want.

*Notice how you have changed after a tragedy or crisis. Many people report having more confidence in themselves after a crisis and some even have a deeper appreciation for life. Get what you can out of these tough times.

*Take care of yourself! Get enough food, sleep, and exercise to keep yourself healthy. This is especially important during times of stress.

*Lastly, seek professional help if you feel that the situation is too hard for you to handle on your own. A licensed mental health professional, such as a counselor or psychologist, can help you develop a strategy for moving forward in your life.

Co-Occuring Disorders

Thursday, April 2nd, 2009

Definition
Just as the field of treatment for substance use and mental disorders has evolved to become more precise, so too has the terminology used to describe people with both substance use and mental disorders. The term co-occurring disorders replaces the terms dual disorder or dual diagnosis. These latter terms, though used commonly to refer to the combination of substance use and mental disorders, are confusing in that they also refer to other combinations of disorders (such as mental disorders and mental retardation).

Furthermore, the terms suggest that there are only two disorders occurring at the same time, when in fact there may be more. Clients with co-occurring disorders (COD) have one or more disorders relating to the use of alcohol and/or other drugs of abuse as well as one or more mental disorders. A diagnosis of co-occurring disorders occurs when at least one disorder of each type can be established independent of the other and is not simply a cluster of symptoms resulting from the one disorder.

Although co-occurring disorder is the most current term used professionally, for the purposes of this article, dual disorders will be used interchangeably.

The acronym MICA, which represents the phrase Mentally Ill Chemical Abusers, is occasionally used to designate people who have a COD and a markedly severe and persistent mental disorder such as schizophrenia or bipolar disorder. A preferred definition is mentally ill chemically affected people, since the word affected better describes their condition and is not pejorative. Other acronyms include: MISA (mentally ill substance abusers), CAMI (chemical abuse and mental illness), SAMI (substance abuse and mental illness), MISU (mentally ill substance using), MICD (mentally ill chemically dependent) and ICOPSD (individuals with co-occurring psychiatric and substance disorders).

Common examples of co-occurring disorders include the combinations of major depression with cocaine addiction, alcohol addiction with panic disorder, alcoholism and polydrug addiction with schizophrenia, and borderline personality disorder with episodic polydrug abuse. Although the focus of this is on dual disorders, some patients have more than two disorders. The principles that apply to dual disorders generally apply also to multiple disorders.

The combinations of COD problems and psychiatric disorders vary along important dimensions, such as severity, chronicity, disability, and degree of impairment in functioning. For example, the two disorders may each be severe or mild, or one may be more severe than the other. Indeed, the severity of both disorders may change over time. Levels of disability and impairment in functioning may also vary.

Thus, there is no single combination of dual disorders; in fact, there is great variability among them. However, patients with similar combinations of dual disorders are often encountered in certain treatment settings.

More than half of all adults with severe mental illness are further impaired by substance use disorders (abuse or dependence related to alcohol or other drugs).

Compared to patients who have a mental health disorder or a COD use problem alone, patients with dual disorders often experience more severe and chronic medical, social, and emotional problems. Because they have two disorders, they are vulnerable to both COD relapse and a worsening of the psychiatric disorder. Further, addiction relapse often leads to psychiatric decompensation, and worsening of psychiatric problems often leads to addiction relapse. Thus, relapse prevention must be specially designed for patients with dual disorders. Compared with patients who have a single disorder, patients with dual disorders often require longer treatment, have more crises, and progress more gradually in treatment.

Psychiatric disorders most prevalent among dually diagnosed patients include mood disorders, anxiety disorders, personality disorders, and psychotic disorders.

Symptoms The symptoms of co-occurring disorder include those associated with substance abuse along with those of psychiatric disorders mentioned previously.

Substance abuse is a maladaptive pattern of substance use manifested by recurrent and significant adverse consequences related to the repeated use of substances. Individuals who abuse substances may experience such harmful consequences of substance use as repeated failure to fulfill roles for which they are responsible, legal difficulties, or social and interpersonal problems. It is important to note that the chronic use of an illicit drug still constitutes a significant issue for treatment even when it does not meet the criteria for substance abuse.

For individuals with more severe or disabling mental disorders, as well as for those with developmental disabilities and traumatic brain injuries, even the threshold of substance use that might be harmful (and therefore defined as abuse) may be significantly lower than for individuals without such disorders. Furthermore, the more severe the disability, the lower the amount of substance use that might be harmful.

People with dual disorders are at high risk for many additional problems such as symptomatic relapses, hospitalizations, financial problems, social isolation, family problems, homelessness, suicide, violence, sexual and physical victimization, incarceration, serious medical illnesses, such as HIV and hepatitis B and C, and early death. Any one of these problems complicates the treatment of co-occurring disorder.

Causes The common wisdom among mental health and medical professionals is that both disorders are biologically based and related to the brain. Sometimes the mental problem occurs first. This can lead people to use alcohol or drugs that make them feel better temporarily. Sometimes the substance abuse occurs first. Over time, that can lead to emotional and mental problems.

Mental disorders and addiction are each a dynamic process, with fluctuations in severity, rate of progression, and symptom manifestation and with differences in the speed of onset. Both disorders are greatly influenced by several factors, including genetic susceptibility, environment, and pharmacologic influences. Certain people have a high risk for these disorders (genetic risk); some situations can evoke or help to sustain these disorders (environmental risk); and some drugs are more likely than others to cause psychiatric or substance use disorder problems (pharmacologic risk).

Treatment To provide appropriate treatment for this complex diagnosis, the Substance Abuse and Mental Health Services Administration (SAMHSA) of the US Department of Health and Human Services recommends integrated treatment of people with COD based on current research that supports the efficacy of this treatment. Integrated treatment is a means of coordinating substance abuse and mental health interventions to treat the whole person more effectively in the context of a primary treatment relationship or service setting.

Integrated Dual Disorders Treatment occurs when a person receives combined treatment for mental illness and substance use from the same clinician or treatment team. It helps people develop hope, knowledge, skills, and the support they need to manage their problems and to pursue meaningful life goals. A person is receiving integrated treatment because their clinician or treatment team will do several things at the same time, including:

  • Help the person think about the role that alcohol and other drugs play in their life. This should be done confidentially, without any negative consequences. People feel free to discuss these issues when the discussion is confidential, nonjudgmental, and not tied to legal consequences.
  • Offer the person a chance to learn more about alcohol and drugs, to learn about how they interact with mental illnesses and with medications, and to discuss their own use of alcohol and drugs.
  • Help the person become involved with supported employment and other services that may help the process of recovery.
  • Help the person identify and develop recovery goals. If the person decides that the use of alcohol or drugs may be a problem, a counselor trained in integrated dual disorders treatment can help the person identify and develop personalized recovery goals. This process includes learning about steps toward recovery from both illnesses.
  • Provide special counseling specifically designed for people with dual disorders. If the person decides that the use of alcohol or drugs may be a problem, a trained counselor can provide special counseling specifically designed for people with dual disorders. This can be done individually, with a group of peers, with family members, or with a combination of these.

Successful strategies with important implications for clients with COD include interventions based on addiction work in contingency management, cognitive-behavioral therapy (CBT), relapse prevention, and motivational interviewing.

The Mental Health System

Most states have an assortment of public mental health centers that have a wide range of services. Mental health services are provided by a variety of mental health professionals including psychiatrists; psychologists; clinical social workers; clinical nurse specialists; certified substance abuse counselors (CSACs); other therapists and counselors including marriage, family, and child counselors; and paraprofessionals.

These mental health personnel work in a variety of settings, using a variety of theories about the treatment of specific psychiatric disorders. Different types of mental health professionals (for example, social workers and MFCCs) have differing perspectives; moreover, practitioners within a given group often use different approaches.

A major strength of the mental health system is the comprehensive array of services offered, including counseling, case management, partial hospitalization, inpatient treatment, vocational rehabilitation, and a variety of residential programs. The mental health system has a relatively large variety of treatment settings. These settings are designed to provide treatment services for patients with acute, subacute, and long-term symptoms. Acute services are provided by personnel in emergency rooms and hospital units of several types and by crisis—line personnel, outreach teams, and mental health law commitment specialists. Hospitals, day treatment programs, mental health center programs, and several types of individual practitioners provide sub-acute. Long-term settings include mental health centers, residential units, and practitioners’ offices. Clinicians vary with regard to academic degrees, styles, expertise, and training.

The Addiction Treatment System

Individuals with COD are found in all addiction treatment settings, at every level of care. Although some of these individuals have serious mental illness and/or are unstable or disabled, many of them have relatively stable disorders of mild to moderate severity. As substance abuse treatment programs serve the increasing number of clients with COD, the essential program elements required to meet their needs must be defined clearly and set in place.

Essential components of treatment for substance abuse agencies with COD clients:

  1. Screening, assessment, and referral
  2. Mental and physical health consultation
  3. The use of a prescribing onsite psychiatrist
  4. Medication and medication monitoring
  5. Psychoeducational classes
  6. Onsite double trouble groups
  7. Offsite dual recovery mutual self-help groups. These elements are applicable in both residential and outpatient programs.

Screening, Assessment, and Referral

All substance abuse treatment programs should have in place appropriate procedures for screening, assessing, and referring clients with COD. It is the responsibility of each provider to identify clients with both mental—and substance—use disorders, and assure that they have access to the care needed for each disorder.

Screening is a formal process of testing to determine whether a client does or does not warrant further attention at the current time in regard to a particular disorder and, in this context, the possibility of a co-occurring substance use or mental disorder. The screening process for COD seeks to answer a “yes” or “no” question: Does the substance abuse (or mental health) client being screened show signs of a possible mental health (or substance abuse) problem?

Assessment is a process for defining the nature of that problem and developing specific treatment recommendations for addressing the problem. A basic assessment consists of gathering key information and engaging in a process with the client that enables the counselor to understand the client’s readiness for change, problem areas, COD diagnoses, disabilities, and strengths. This typically involves a clinical examination of the functioning and well-being of the client and includes a number of tests and written and oral exercises. The COD diagnosis is established by referral to a psychiatrist, clinical psychologist, or other qualified healthcare professional. Assessment of the client with COD is an ongoing process that should be repeated over time to capture the changing nature of the client’s status.

Some intake information includes:

  • Background: family, trauma history, history of domestic violence (either as a batterer or as a battered person), marital status, legal involvement and financial situation, health, education, housing status, strengths and resources, and employment.
  • Substance use: age of first use, primary drugs used (including alcohol, patterns of drug use, and treatment episodes), and family history of substance use problems.
  • Mental health problems: family history of mental health problems, client history of mental health problems including diagnosis, hospitalization and other treatment, current symptoms and mental status, medications, and medication adherence.

A comprehensive assessment serves as the basis for an individualized treatment plan. Appropriate treatment plans and treatment interventions can be quite complex, depending on what might be discovered in each domain. This leads to another fundamental principle: There is no single, correct intervention or program for individuals with COD. Rather, the appropriate treatment plan must be matched to individual needs according to these multiple considerations.

Mental and Physical Health Consultation

A physical and mental health consultation serves individuals with COD by determining the physical and mental health challenges and incorporates the necessary treatment(s) into patient services.

Prescribing an Onsite Psychiatrist

An onsite addiction treatment psychiatrist can improve treatment retention and decrease substance use among patients. The onsite psychiatrist brings diagnostic, medication, and psychiatric counseling services directly to the location clients are based at for the major part of their treatment. This approach often is the most effective way to overcome barriers presented by offsite referral, including distance and travel limitations, the inconvenience of enrolling in another agency and of the separation of clinical services (more “red tape”), fears of being seen as “mentally ill” (if referred to a mental health agency), cost, and the difficulty of becoming comfortable with different staff.

Medication and Medication Monitoring

Many clients with COD require medication to control their psychiatric symptoms and to stabilize their psychiatric status.

Pharmacological advances over the past decade have produced antipsychotic, antidepressant, anticonvulsant, and other medications with greater effectiveness and fewer side effects. With the support available from better medication regimens, many people who once would have been too unstable for substance abuse treatment, or institutionalized with a poor prognosis, have been able to lead more functional lives.

Psychoeducational Classes

Psychoeducational classes on mental and substance use disorders are important elements in basic COD programs. These classes typically focus on the signs and symptoms of mental disorders, medication, and the effects of mental disorders on substance abuse problems. Psychoeducational classes of this kind increase client awareness of their specific problems and do so in a safe and positive context.

Relapse prevention education presents strategies designed to help clients become aware of cues or “triggers” that make them more likely to abuse substances and help them develop alternative coping responses to those cues. Some providers suggest the use of “mood logs” that clients can use to increase their consciousness of the situational factors that underlie the urge to use or drink.

Onsite Double Trouble Groups

Onsite groups such as “Double Trouble” provide a forum for discussion of the interrelated problems of mental disorders and substance abuse, helping participants to identify triggers for relapse. Clients describe their psychiatric symptoms (such as hearing voices) and their urges to use drugs. They are encouraged to discuss, rather than to act on, these impulses. Double Trouble groups also can be used to monitor medication adherence, psychiatric symptoms, substance use, and adherence to scheduled activities. Double Trouble provides a constant framework for assessment, analysis, and planning. Through participation, the individual with COD develops perspective on the interrelated nature of mental disorders and substance abuse and becomes better able to view his or her behavior within this framework.

Dual Recovery Mutual Self-Help Groups (Offsite)

These offsite self-help groups exist in many communities. Substance abuse treatment programs can refer clients to dual recovery mutual self-help groups, which are tailored to the special needs of a variety of people with COD. These groups provide a safe forum for discussion about medication, mental health, and substance abuse issues in an understanding, supportive environment wherein coping skills can be shared.

The dual recovery mutual self-help movement is emerging from two cultures: the 12-Step fellowship recovery movement and, more recently, the culture of the mental health consumer movement. In keeping with traditional 12-Step principles and traditions, dual recovery 12-Step fellowships do not provide specific clinical or counseling interventions, classes on psychiatric symptoms, or any services similar to case management. Dual recovery fellowships maintain a primary purpose of members helping one another achieve and maintain dual recovery, prevent relapse, and carry the message of recovery to others who experience dual disorders. Dual recovery 12-Step members who take turns chairing their meetings are members of their fellowship as a whole.

Substance abuse groups include the 12-step program of Alcoholics Anonymous (AA); Narcotics Anonymous (NA), Cocaine Anonymous (CA), and so on, can provide needed support and encouragement for patients in treatment. More importantly, these services are widespread nationally and internationally. While self-help programs are not considered treatment per se, they are integral adjuncts to professional treatment services.

Outpatient Substance Abuse Treatment Programs for Clients with COD

Treatment for substance abuse occurs most frequently in outpatient settings—a term that includes a wide variety of disparate programs. Some offer several hours of treatment each week, which can include mental health and other support services as well as individual and group counseling for substance abuse; others provide minimal services, such as only one or two brief sessions to give clients information and refer them elsewhere. Some agencies offer intensive outpatient programs that provide services several hours per day and several days per week. Typically, treatment includes individual and group counseling, with referrals to appropriate community services.

Screening and assessment are used to make two essential decisions—about the stability of the individual with COD to remain in an inpatient, outpatient or appropriate alternative treatment setting and the needed mental health services. A centralized intake team is a useful approach to screening and assessment, providing a common point of entry for many clients entering treatment.

Once admitted to treatment, clients need regular reassessment as reductions in acute symptoms of mental distress and substance abuse may precipitate other changes. Periodic assessment will provide measures of client change and enable the provider to adjust service plans as the client progresses through treatment. Then careful assessment will help to identify those clients who require more secure inpatient treatment settings (such as clients who are actively suicidal or homicidal), as well as those who require 24-hour medical monitoring, those who need detoxification, and those with serious substance use disorders who may require a period of abstinence or reduced use before they can engage actively in all treatment components.

Discharge planning is important to maintain gains achieved through outpatient care. Clients with COD leaving an outpatient substance abuse treatment program have a number of continuing care options. These options include mutual self-help groups, relapse prevention groups, continued individual counseling, mental health services (especially important for people who will continue to require medication), as well as intensive case management monitoring and supports. A carefully developed discharge plan, produced in collaboration with the person with COD, will identify and match their needs with community resources, providing the supports needed to sustain the progress achieved in outpatient treatment.

Individuals with COD often need a range of services besides substance abuse treatment and mental health services. Generally, prominent needs include housing and case management services to establish access to community health and social services. These can be essential to the successful recovery of the person with COD.

It is imperative that discharge planning for the client with COD ensures continuity of psychiatric assessment and medication management, without which client stability and recovery will be severely compromised. Relapse prevention interventions after outpatient treatment need to be modified so that the client can recognize symptoms of psychiatric or substance abuse relapse on her own and can call on a learned repertoire of symptom management techniques (such as self-monitoring, reporting to a “buddy,” and group monitoring). This also includes the ability to access assessment services rapidly, since the return of psychiatric symptoms can often trigger substance abuse relapse.

The Medical System

Although not substance abuse treatment settings per se, acute care and other medical settings are included here because important substance abuse and mental health treatment do occur in medical units. Acute care refers to short-term care provided in intensive care units, brief hospital stays, and emergency rooms (ERs). Providers in acute care settings usually are not concerned with treating substance use disorders beyond detoxification, stabilization, and/or referral.

In other medical settings, such as primary care offices, providers generally lack the resources to provide any kind of extensive substance abuse treatment, but may be able to provide brief interventions and treatment referrals.

Primary health-care providers (physicians and nurses) have historically been the largest single point of contact for patients seeking help with psychiatric and COD use disorders. Physicians and nurses are uniquely qualified to manage life-threatening crises and to treat medical problems related and unrelated to psychiatric and substance use disorders. And because they are in contact with such large numbers of patients, they have an exceptional opportunity to screen and identify patients with psychiatric and COD disorders. At that point, the person with COD can be referred for appropriate services in the proper setting.

Sources:

  • American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition
  • Office for Treatment Improvement, Alcohol, Drug Abuse, and Mental Health Administration
  • Substance Abuse and Mental Health Services Administration (2005)
  • Hospital and Community Psychiatry
  • Dual Diagnosis of Major Mental Illness and Substance Disorder
  • Journal of the American Medical Association
  • Journal of Addictive Diseases
  • Archives of General Psychiatry
  • Center for Substance Abuse Treatment
  • Charney DA, Paraherakis AM, Gill KJ. Integrated treatment of comorbid depression and substance use disorders. Journal of Clinical Psychiatry. 62((9)):672-677; 2001.
  • Saxon AJ, Calsyn DA. Effects of psychiatric care for dual diagnosis patients treated in a drug dependence clinic. American Journal of Drug and Alcohol Abuse. 21((3)):303-313; 1995.
  • Etheridge RM, Hubbard RL, Anderson J, Craddock SG, Flynn PM. Treatment structure and program services in the Drug Abuse Treatment Outcome Study (DATOS). Psychology of Addictive Behavior. 11((4)):244-260; 1997.
  • Simpson DD, Joe GW, Rowan-Szal GA. Drug abuse treatment retention and process effects on follow-up outcomes. Drug and Alcohol Dependence. 47((3)):227-235; 1997b.

Post Traumatic Stress Disorder

Monday, March 2nd, 2009

Definition
Post-Traumatic Stress Disorder (PTSD) is an anxiety disorder that may develop after exposure to a terrifying event or ordeal in which severe physical harm occurred or was threatened. Traumatic events that may trigger PTSD include violent personal assaults, natural or unnatural disasters, accidents, or military combat.

Those who may experience PTSD include military troops who served in wars; rescue workers for catastrophes like the 2001 terrorist attacks on New York City and Washington, D.C.; survivors of the Oklahoma City bombing; survivors of accidents, rape, physical or sexual abuse, and other crimes; immigrants fleeing violence in their countries; survivors of earthquakes, floods, and hurricanes; and those who witness traumatic events. Family members of victims can develop the disorder as well.

PTSD affects about 7.7 million American adults, but it can occur at any age, including childhood. Women are more likely to develop the disorder than men, and there is some evidence that it may run in families. PTSD is frequently accompanied by depression, substance abuse, or anxiety disorders. When other conditions are appropriately diagnosed and treated, the likelihood of successful treatment increases.

Roughly 30 percent of Vietnam veterans developed PTSD. The disorder also has been detected among veterans of the Gulf War, with some estimates running as high as 8 percent.

Complex PTSD

Complex PTSD, also known as disorder of extreme stress, is found among individuals who have been exposed to prolonged traumatic circumstances, especially during childhood, such as childhood sexual abuse. Research shows that many brain and hormonal changes may occur as a result of early, prolonged trauma, and contribute to troubles with learning, memory, and regulating emotions. Combined with a disruptive, abusive home environment, these brain and hormonal changes may contribute to severe behavioral difficulties such as eating disorders, impulsivity, aggression, inappropriate sexual behavior, alcohol or drug abuse, and other self-destructive actions, as well as emotional regulation (such as intense rage, depression, or panic) and mental difficulties (such as scattered thoughts, dissociation, and amnesia). As adults, these individuals often are diagnosed with depressive disorders, personality disorders, or dissociative disorders. Treatment may progress at a much slower rate, and requires a sensitive and structured program delivered by a trauma specialist.

Symptoms Many people with PTSD tend to re-experience the ordeal that set the disease in motion, especially when they are exposed to events or objects reminiscent of the trauma. Anniversaries of the event can also trigger symptoms. People with PTSD also experience emotional numbness, sleep disturbances, anxiety, intense guilt, depression, irritability, or outbursts of anger. Most people with PTSD try to avoid any reminders or thoughts of the ordeal. PTSD is diagnosed when symptoms last more than one month.

Symptoms associated with reliving the traumatic event:

  • Having bad dreams about the event or something similar
  • Behaving or feeling as if the event were actually happening all over again (known as flashbacks)
  • Having a lot of emotional feelings when reminded of the event
  • Having a lot of physical sensations when reminded of the event (heart pounds or misses a beat, sweating, difficulty breathing, feeling faint, feeling a loss of control)

Symptoms related to avoidance of reminders of the traumatic event:

  • Avoiding thoughts, conversations, or feelings about the event
  • Avoiding people, activities, or places associated with the event
  • Having difficulty remembering an important part of the original trauma

Changes frequently made after the event:

  • Loss of interest in things previously considered important
  • Feeling detached from people
  • Feeling emotionally numb and finds it hard to have loving feelings even toward those who are close
  • Difficulty falling or staying asleep
  • Irritability and anger
  • Difficulty concentrating
  • Feeling that one is not going to live long and there is no reason to plan for the future
  • Feeling easily startled
  • Always on guard

Medical or emotional issues:

  • Stomach problems
  • Intestinal problems
  • Gynecological problems
  • Weight gain or loss
  • Chronic pain (back, neck, pelvic area in women)
  • Problems getting to sleep
  • Problems staying asleep
  • Headaches
  • Skin rashes and other problems
  • Irritability, quick temper, other anger problems
  • Nightmares
  • Depression
  • Lack of energy, chronic fatigue
  • Alcoholism and other substance use problems
  • General anxiety
  • Panic attacks

Causes People who have suffered childhood abuse or other previous traumatic experiences are more likely to develop the disorder. And people who experience emotional distancing may be more prone to PTSD.

Studies in animals and humans have pinpointed the brain areas involved in anxiety and fear, which are important for understanding anxiety disorders such as PTSD. Fear, an emotion that evolved to deal with danger, causes an automatic, rapid protective response in the body. The fear response is coordinated by a small structure deep inside the brain, called the amygdala. The amygdala, is a complicated structure, and research suggests that posttraumatic stress disorder may be associated with abnormal activation of the amygdala.

Once fear is conditioned in the amygdala, it is hard to change. However, the neural pathways from the amygdala to the hippocampus and to cortical regions such as the frontal lobes allow its suppression until triggered. Fear quickly returns when the individual is re-exposed. An increase in stressors seems to affect the fear-inducing and the fear-inhibiting pathways. High stress levels decrease the capacity to suppress fear, while increasing the ability to induce it. Thus, the fear induced by re-exposure to traumatic material indicates a failure of inhibition on the part of the hippocampus, and is evidence that the traumatic episode is not integrated as a narrative, spatio-temporal event in autobiographical memory. Furthermore, the heightened sensitivity of exposure of PTSD patients to trauma-related material results in an increase in fearfulness in response to stimuli that are not truly life threatening.

Studies using MRI in PTSD have measured volume of the hippocampus, a brain structure involved in learning and memory. Patients with combat-related PTSD had an 8 percent decrease in right hippocampal volume when compared with controls. A decrease of 12 percent in left hippocampal volume was found in patients with a history of PTSD related to severe childhood physical and sexual abuse. Reduced hippocampal volume was associated with dissociative symptoms in women who had a history of childhood sexual abuse.

People with PTSD tend to have abnormally high levels of key hormones involved in response to stress. A person in danger produces high levels of natural opiates, which can temporarily mask pain. Scientists have found that people with PTSD continue to produce those higher levels even after the danger has passed, which might lead to the blunted emotions associated with the condition.

Some studies have shown that cortisol levels are lower than normal and epinephrine and norepinephrine are higher than normal. Norepinephrine is a neurotransmitter released during stress, and one of its functions is to activate the hippocampus, the brain structure involved with organizing and storing information for long-term memory.

This action of norepinephrine is thought to be one reason why people can remember emotionally arousing events better than other situations. Under the extreme stress of trauma, norepinephrine may act longer or more intensely on the hippocampus, leading to the formation of abnormally strong memories that are then experienced as flashbacks or intrusions.

Treatment Treatment for PTSD typically begins with a detailed evaluation, and development of a treatment plan that meets the unique needs of the survivor. PTSD-specific-treatment begins only when the survivor is safely removed from the crisis situation. Other strategies for treatment include:

  • Educating trauma survivors and their families about how persons get PTSD, how PTSD affects survivors and their loved ones, and other problems commonly associated with PTSD symptoms. Understanding that PTSD is a medically recognized anxiety disorder is essential for effective treatment.
  • Exposure to the event via imagery allows the survivor to re-experience the event in a safe, controlled environment. A professional can carefully examine reactions and beliefs in relation to that event.
  • Examining and resolving strong feelings such as shame, anger, or guilt, which are common among survivors of trauma.
  • Teaching the survivor to cope with post-traumatic memories, reminders, reactions, and feelings without becoming overwhelmed or emotionally numb. Trauma memories usually do not go away entirely as a result of therapy, but new coping skills can make them more manageable.

Medications

A number of medications that were originally approved for depression have been found effective in healing post-traumatic stress disorder. If an antidepressant is prescribed, it will need to be taken for several weeks before symptoms start to fade. It is important not to get discouraged and stop taking these medications before they’ve had a chance to work.

Some of the newest antidepressants are called selective serotonin reuptake inhibitors, or SSRIs. These medications act in the brain on a chemical messenger called serotonin. SSRIs tend to have fewer side effects than older antidepressants. While some patients report feeling slightly nauseated or jittery when taking SSRIs, symptoms disappear with time. Some people also experience sexual dysfunction when using some of these medications. An adjustment in dosage or a switch to another SSRI will usually correct problems. It is important to discuss side effects with your doctor.

Fluoxetine, sertraline, fluvoxamine, paroxetine, and citalopram are among the SSRIs commonly prescribed for PTSD. These medications are given at a low dose and gradually increased until they reach a therapeutic level.

Similarly, antidepressant medications called tricyclics are given at low doses and gradually increased. Tricyclics have been around longer than SSRIs and have been more widely studied for treating anxiety disorders. They are as effective as the SSRIs, but many physicians and patients prefer the newer drugs because the tricyclics sometimes cause dizziness, dry mouth, drowsiness, and weight gain.

Psychotherapy

Cognitive-behavioral therapy (CBT) works to change emotions, thoughts, and behaviors. Exposure therapy is one form of CBT unique to trauma treatment—this uses careful, repeated, detailed imagining of the trauma in a safe, controlled context. In some cases, trauma memories or reminders can be confronted all at once (flooding). And in other cases, it is preferable to work gradually up to the most severe trauma by using relaxation techniques and by taking the trauma one piece at a time (desensitization).

Along with exposure, CBT includes learning skills for coping with anxiety (for example, breathing retraining or biofeedback) and negative thoughts (cognitive restructuring), managing anger, preparing for stress reactions (stress innoculation), handling future trauma symptoms, as well as addressing urges to use alcohol or drugs (relapse prevention), and communicating and relating effectively with people (social skills or marital therapy).

Eye movement desensitization and reprocessing (EMDR) is a relatively new treatment of traumatic memories that involves elements of exposure therapy and cognitive behavioral therapy, combined with techniques (sounds, eye movements, hand taps) that create an alteration of attention. There is some evidence that the therapeutic element unique to EMDR, attentional alteration, may be helpful in accessing and processing traumatic material.

Group treatment is an ideal therapeutic setting because trauma survivors are able to risk sharing traumatic material in a safe environment. As group members achieve greater understanding and resolution of their trauma, they often feel more confident and able to trust. As they discuss and share trauma-related shame, guilt, fear, rage, doubt, and self-condemnation, they prepare themselves to focus on the present rather than the past. Telling one’s story and directly facing the grief, guilt, and anxiety related to trauma enables many survivors to cope with their symptoms, memories, and other aspects of life.

Brief psychodynamic psychotherapy focuses on the emotional conflicts caused by the traumatic event, particularly in relation to early life experiences. Through the retelling of the traumatic event to a calm and empathic counselor, the survivor achieves a greater sense of self-esteem, develops effective ways of thinking and coping, and more successfully deals with the intense emotions that emerge during therapy. The therapist helps the survivor identify current life situations that set off traumatic memories and worsen PTSD symptoms.

Is Internet Addiction Even Real?

Monday, January 12th, 2009

The Internet is unlike anything we have ever seen before. It is a socially connecting device that is socially isolating at the same time. With the increasing number of users and the social problems that people are finger pointing at, it is not surprising that there is an uprising concern about the use of Internet.

However, no research has yet established that there is a disorder of Internet addiction that is separable from problems such as loneliness or pathological gambling, or that a passion for using the Internet is long-lasting.

Much of the original research was based upon the weakest type of research methodology, namely exploratory surveys with no clear hypothesis or rationale backing them. Therefore, we cannot establish causal relationships between specific behaviors and their cause.

Years have gone by and there are more than a few studies out there looking at Internet addiction. Yet none of them agree on a single definition for this problem, and all of them vary widely in their reported results of how much time an “addict” spends online. If they cannot even get these basics down, it is not surprising the research quality still suffers.

For now, this and other questions about Internet use will remain unanswered until more controlled studies are done.

Do some people have problems spending too much time online?

Sure they do. Some people also spend too much time reading, watching television, and working, and ignore family, friendships, and social activities. That does not suggest they have a TV addiction disorder, book addiction, and work addiction that is legitimate mental disorders in the same category as schizophrenia and depression. It is the tendency of some mental health professionals and researchers to want to label everything they see as potentially harmful with a new diagnostic category. Unfortunately, this causes more harm than it helps people.

Some people online who think they are addicted could possibly be suffering from desires not to want to deal with other problems in their lives. These problems could include a mental disorder (depression, anxiety, etc.), a serious health problem or disability, or a relationship problem. In this case, it is no different than turning on the TV so you won’t have to talk to your spouse, or going “out with the boys” for a few drinks so you don’t have to spend time at home. Nothing is different except the modality.

On the other hand, some people who spend time online without any other problems present may suffer from compulsive over-use. Compulsive behaviours, however, are already covered by existing diagnostic categories and treatment would be similar. It is not the technology (whether it be the Internet, a book, the telephone, or the television) that is important or addicting – it is the behavior. And behaviors are easily treatable by cognitive-behavioural techniques in psychotherapy.

Is it possible for people to become addicted to chat rooms?

As explained above, I will now use the word addiction in a different manner.

Time alone cannot be an indicator of being addicted or engaging in compulsive behavior. Time must be taken in context with other factors, such as whether you are a college student (who, as a whole, proportionally spend a greater amount of time online), whether it is a part of your job, whether you have any pre-existing conditions (such as another mental disorder), whether you have problems or issues in your life which may be causing you to spend more time online (e.g., using it to “get away” from life’s problems, a bad marriage, difficult social relations), etc. So talking about whether you spend too much time online without this important context is useless.

There are evidence that suggests that the time people spend chatting online is phasic and can be explained in terms of three phases:

Stage I: Enchantment (Obsession)
Stage II: Disillusionment (Avoidance)
Stage III: Balance (Normal)

That is to say that people first are enchanted by the activity (characterized by some as obsession) especially when they are new users, followed by disillusionment with chatting and a decline in usage, and then a balance was reached where the level of chat activity normalized.

What can lead to such an addiction?

How do people get caught up in the Internet? For one thing, human beings are curious. People like to see more and do more. People like to feel competent and in control. Online, they can act in ways that are exciting and they can do so without leaving their chair of being with a real person. Especially in chat rooms and a virtual society - accountability, supervision and social consequences are almost non-existent.

People also like to feel better and they don’t like to feel bad. We like to do things that feel good and avoid things that feel worse. We especially like doing pleasurable things more and more.

On the Internet, people do not have to go out and find real people and have an honest relationship. They can stay in their own chair and explore endless activities. They can walk away and come right back. There is always something happening.

People will even miss you and ask you to come back.

The seduction and addictive nature of the chat rooms can be understood primarily in terms of a behavior modification process called a variable reinforcement schedule. That means you don’t know how much of a reward you will get and when for your behavior (ie. praises, expressions of longing, admiration, intimacy, true friendships, etc). And a variable reinforcement schedule is the most addictive reward system.

Being on the Internet is not necessarily about having a good time. Being on-line might make you feel better but it might just change how you feel. It can be an escape from reality that isn’t necessarily better for you.

Prolonged chats on-line and mouse clicking on the Internet will produce a dissociative state whereby Internet users can separate from reality and enter cyber reality. Anyone with children has seen how children can watch television for countless hours. Children and even adults watching television long enough will enter a “hypnotic trance.” They “meld” into the television and disconnect from reality.

People can disappear into a good book or a movie, but there is always an end to a book or a movie. The Internet is especially addictive because it is endless, interactive, social and exploding with never ending images and information. The Internet offers exciting relationships 24 hours a day all over the world.

Limited use is a form or healthy recreation or escape. Prolonged and repeated use can create problems.

What do you think is the pull or the attraction for many young people today to communicate and express themselves and make friends via chat rooms as opposed to meeting people the old fashioned way?

Nearly 20% of the people going on-line will encounter one or more of the following problems.

    * Personal neglect
* Social anxiety
* Lack self esteem and self confidence
* Compulsive checking and “clicking”
* Isolation and avoidance from people
* Depression
* Relationship problems
* Academic failure

Apart from that, meeting real people and developing friendships takes a longer time and much more effort and in this century, I see young people having heavier schedules than the average adult! Piano lessons, tuition classes for all subjects, competitive sports, you name it.

Meeting people online also seems to be more convenient and cost effective for young people. They don’t have to negotiate with their parents for money, transportation and curfew time.

To a certain extend, meeting real people means taking a risk. A risk of getting hurt, embarrassed, humiliated and many more. And if that happens online, you can just change your name, age and marital status and just start over.

The reasons why young people choose online chat rooms instead of real life interactions are varied and endless.

Furthermore, some people do have serious challenges in real life social interactions such as social anxiety disorders, depression, shyness, lack self esteem and many more. The most important to bear in mind is to seek professional treatment for it. Help is readily available without needing to create all these hoopla about a new diagnosis.

Nearly any well-trained mental health professional will be able to help to slowly curve the time spent online, and address the problems or concerns that may have contributed to online overuse.

Finally, prevention is more likely to be assured if you maintain balance in your life. People go on-line looking for something missing in their life or they become involved in content and relationships on-line that begin to interfere with important routines, responsibilities and relationships. Making a conscious effort and commitment to a balanced life in crucial.

Bipolar Disorder

Tuesday, November 25th, 2008

Definition
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, and ability to function. These are not the normal ups and downs; the symptoms of bipolar disorder are severe. They can result in damaged relationships, poor job or school performance, and even suicide.

About 5.7 million American adults or about 2.6 percent of the population age 18 and older in any given year have bipolar disorder. Bipolar disorder typically develops in late adolescence or early adulthood. However, some people have their first symptoms during childhood, and some develop them late in life. Bipolar disorder is often not recognized as an illness, and people may suffer for years before it is properly diagnosed and treated. It is a long-term illness that requires careful management throughout the person’s life.

Bipolar disorder causes dramatic mood swings from overly high and, or, irritable to sad and hopeless, and then back again, often with periods of normal mood in between. Severe changes in energy and behavior go along with these changes. The periods of highs and lows are called episodes of mania and depression.

Symptoms Signs and symptoms of manic episode:

  • Increased energy, activity, and restlessness
  • Excessively high, overly good, euphoric mood
  • Extreme irritability
  • Racing thoughts and talking fast, jumping from one idea to another
  • Distractibility or lack of concentration
  • Little sleep needed
  • Unrealistic beliefs in one’s abilities and powers
  • Poor judgment
  • Spending sprees
  • A lasting period of behavior that is different from usual
  • Increased sexual drive
  • Abuse of drugs—cocaine, alcohol, and sleep medications
  • Provocative, intrusive, or aggressive behavior
  • Denial that anything is wrong

A manic episode is diagnosed if elevated mood occurs with three or more of the other symptoms most of the day, nearly every day, for one week or longer. If the mood is irritable, four additional symptoms must be present.

Signs and symptoms of depressive episode:

  • Lasting sad, anxious, or empty mood
  • Feelings of hopelessness or pessimism
  • Feelings of guilt, worthlessness, or helplessness
  • Loss of interest or pleasure in activities once enjoyed, including sex
  • Decreased energy, a feeling of fatigue or of being “slowed down”
  • Difficulty concentrating, remembering, making decisions
  • Restlessness or irritability
  • Sleeping too much, or inability to sleep
  • Change in appetite and, or, unintended weight loss or gain
  • Chronic pain or other persistent physical symptoms not caused by physical illness or injury
  • Thoughts of death or suicide, or suicide attempts

A depressive episode is diagnosed if five or more of these symptoms last most of the day, nearly every day, for a period of two weeks or longer.

A mild to moderate level of mania is called hypomania. Hypomania may feel good to the person who experiences it and may even be associated with good functioning and enhanced productivity. Thus, even when family and friends learn to recognize the mood swings as possible bipolar disorder, the person may deny that anything is wrong. Without proper treatment, however, hypomania can become severe mania in some people or can switch to depression.

Sometimes, severe episodes of mania or depression include symptoms of psychosis. Common psychotic symptoms are hallucinations (hearing, seeing, or otherwise sensing the presence of things not actually there) and delusions (false, strongly held beliefs not influenced by logical reasoning or explained by a person’s usual cultural concepts). Psychotic symptoms in bipolar disorder tend to reflect the extreme mood state at the time. For example, delusions of grandiosity, such as believing one is the president or has special powers or wealth, may occur during mania; delusions of guilt or worthlessness, such as believing that one is ruined and penniless or has committed some terrible crime, may appear during depression. People with bipolar disorder who have these symptoms are sometimes incorrectly diagnosed as having schizophrenia, another severe mental illness.

It may be helpful to think of the various mood states in bipolar disorder as a spectrum. At the bottom end is severe depression, above which is moderate depression and then mild low mood, which many people call the short-lived blues. It is termed dysthymia when it is chronic. Then there is normal or balanced mood, above which comes hypomania (mild to moderate mania), and then severe mania.

In some people, however, symptoms of mania and depression may occur together in what is called a mixed bipolar state. Symptoms of a mixed state often include agitation, trouble sleeping, significant change in appetite, psychosis, and suicidal thinking. A person may have a very sad, hopeless mood while at the same time feeling extremely energized.

Bipolar disorder may appear to be a problem other than mental illness—for instance, alcohol or drug abuse, poor school or work performance, or strained interpersonal relationships. Such problems in fact may be signs of an underlying mood disorder.

Some people with bipolar disorder become suicidal. Anyone who is thinking about committing suicide needs immediate attention, preferably from a mental health professional or a physician. Anyone who talks about suicide should be taken seriously. Risk for suicide appears to be higher earlier in the course of the illness. Therefore, recognizing bipolar disorder early and learning how best to manage it may decrease the risk of death by suicide.

Course of Bipolar Disorder

Episodes of mania and depression typically recur across one’s life span. Between episodes, most people with bipolar disorder are free of symptoms, but as many as one-third of people have some residual symptoms. A small percentage of people experience chronic unremitting symptoms despite treatment.

The classic form of the illness, which involves recurrent episodes of mania and depression, is called bipolar I disorder. Some people, however, never develop severe mania but instead experience milder episodes of hypomania that alternate with depression; this form of the illness is called bipolar II disorder. When four or more episodes of illness occur within a 12-month period, a person is said to have rapid-cycling bipolar disorder. Some people experience multiple episodes within a single week, or even within a single day. Rapid cycling tends to develop later in the course of illness and is more common among women than men.

People with bipolar disorder can lead healthy and productive lives when the illness is effectively treated. Without treatment, however, the natural course of bipolar disorder tends to worsen. Over time a person may suffer more frequent rapid cycling and more severe manic and depressive episodes than those experienced when the illness first appeared. But in most cases, proper treatment can help reduce the frequency and severity of episodes and can help people with bipolar disorder maintain a good quality of life.

Children and Adolescents with Bipolar Disorder

Both children and adolescents can develop bipolar disorder. It is more likely to affect the children of parents who have the illness.

Unlike many adults with bipolar disorder, whose episodes tend to be more clearly defined, children and young adolescents with the illness often experience very fast mood swings between depression and mania many times within a day. Children with mania are more likely to be irritable and prone to destructive tantrums than to be overly happy and elated. Mixed symptoms also are common in youths with bipolar disorder. Older adolescents who develop the illness may have more classic, adult-type episodes and symptoms.

Bipolar disorder in children and adolescents can be hard to tell apart from other problems that may occur in these age groups. For example, while irritability and aggressiveness can indicate bipolar disorder, they also can be symptoms of attention-deficit hyperactivity disorder, conduct disorder, oppositional defiant disorder, or of other types of mental disorders that are more common among adults, such as major depression or schizophrenia. Drug abuse also may lead to such symptoms.

For any illness, however, effective treatment depends on appropriate diagnosis. Children or adolescents with emotional and behavioral symptoms should be carefully evaluated by a mental-health professional.

Conditions that Can Co-occur with Bipolar Disorder

Alcohol and drug abuse are very common among people with bipolar disorder. Research findings suggest that many factors may contribute to these substance abuse problems, including self-medication of symptoms, mood symptoms either brought on or perpetuated by substance abuse, and risk factors that may influence the occurrence of both bipolar disorder and substance-use disorders. Treatment for co-occurring substance abuse, when present, is an important part of the overall treatment plan.

Anxiety disorders, such as post-traumatic stress disorder and obsessive-compulsive disorder, also may be common in people with bipolar disorder. Co-occurring anxiety disorders may respond to treatments used for bipolar disorder, or they may require separate treatment.

Causes Scientists are learning about the possible causes of bipolar disorder. Most scientists now agree that there is no single cause for bipolar disorder; rather, many factors act together to produce the illness.

Because bipolar disorder tends to run in families, researchers have been seeking specific genes that may increase a person’s chance of developing the illness. But genes are not the whole story. Studies of identical twins, who share all the same genes, indicate that both genes and other factors play a role in bipolar disorder. If bipolar disorder was caused entirely by genetics, then the identical twin of someone with the illness would always develop the illness, and research has shown that this is not the case. But if one twin has bipolar disorder, the other twin is more likely to develop the illness than is another sibling.

In addition, findings suggest that bipolar disorder, like other mental illnesses, does not occur because of a single gene. It is likely that many genes act together, in combination with other factors such as the person’s environment. Finding these genes, each of which contributes only a small amount toward the vulnerability to bipolar disorder, has been extremely difficult. But scientists expect that the advanced research tools now being used will lead to these discoveries and to new and better treatments for bipolar disorder.

Brain-imaging studies are helping scientists learn what goes wrong in the brain to produce bipolar disorder and other mental illnesses. New brain-imaging techniques allow researchers to take pictures of the living brain at work, to examine its structure and activity, without the need for surgery or other invasive procedures. These techniques include magnetic resonance imaging (MRI), positron emission tomography (PET), and functional magnetic resonance imaging (fMRI). There is evidence from imaging studies that the brains of people with bipolar disorder may differ from the brains of healthy individuals. As the differences are more clearly identified and defined through research, scientists will gain a better understanding of the underlying causes of the illness and eventually may be able to predict which types of treatment will work most effectively.

Treatment Most people with bipolar disorder, even those with the most severe forms, can achieve substantial stabilization of their mood swings and related symptoms with proper treatment. Because bipolar disorder is a recurrent illness, long-term preventive treatment is strongly recommended and almost always indicated. A strategy that combines medication and psychosocial treatment is optimal for managing the disorder over time.

In most cases, bipolar disorder is much better controlled if treatment is continuous rather than on and off. But even when there are no breaks in treatment, mood changes can occur and should be reported immediately to your doctor. The doctor may be able to prevent a full-blown episode by making adjustments to the treatment plan. Working closely with the doctor and communicating openly about treatment concerns and options can make a difference in treatment effectiveness.

In addition, keeping a chart of daily mood symptoms, treatments, sleep patterns, and life events may help people with bipolar disorder and their families to better understand the illness. This chart also can help the doctor track and treat the illness most effectively.

Medications

While primary-care physicians who do not specialize in psychiatry also may prescribe these medications, it is recommended that people with bipolar disorder see a psychiatrist for treatment.

Medications known as mood stabilizers are usually prescribed to help control bipolar disorder. Several types of mood stabilizers are available. In general, people with bipolar disorder continue treatment with mood stabilizers for years. Other medications are added when necessary, typically for shorter periods, to treat episodes of mania or depression.

Lithium, the first mood-stabilizing medication approved by the U.S. Food and Drug Administration (FDA) for treatment of mania, is often very effective in controlling mania and preventing the recurrence of both manic and depressive episodes.

Anticonvulsant medications such as valproate or carbamazepine also can have mood-stabilizing effects and may be especially useful for difficult-to-treat bipolar episodes. Valproate was FDA-approved in 1995 for treatment of mania. Newer anticonvulsant medications, including lamotrigine, gabapentin, and topiramate, are being studied to determine how well they work in stabilizing mood cycles. Anticonvulsant medications may be combined with lithium, or with each other, for maximum effect.

Children and adolescents with bipolar disorder generally are treated with lithium, but valproate and carbamazepine also are used. Researchers are evaluating the safety and efficacy of these and other psychotropic medications in children and adolescents. There is some evidence that valproate may lead to adverse hormone changes in teenage girls and polycystic ovary syndrome in women who begin taking the medication before age 20. Therefore, young female patients taking valproate should be monitored carefully by a physician.

Women with bipolar disorder who wish to conceive or who become pregnant face special challenges due to the possible harmful effects of existing mood stabilizing medications on the developing fetus and the nursing infant. Therefore, the benefits and risks of all available treatment options should be discussed with a clinician skilled in this area. New treatments with reduced risks during pregnancy and lactation are under study.

Research has shown that people with bipolar disorder are at risk of switching into mania or hypomania, or of developing rapid cycling, during treatment with antidepressant medication. Therefore, mood-stabilizing medications generally are required, alone or in combination with antidepressants, to protect people with bipolar disorder from this switch. Lithium and valproate are the most commonly used mood-stabilizing drugs today. However, research studies continue to evaluate the potential mood-stabilizing effects of newer medications.

Atypical antipsychotic medications, including clozapine and ziprasidone, are being studied as possible treatments for bipolar disorder. Evidence suggests clozapine may be helpful as a mood stabilizer for people who do not respond to lithium or anticonvulsants. Other research has supported the efficacy of olanzapine for acute mania, an indication that has recently received FDA approval. Olanzapine may also help relieve psychotic depression.

If insomnia is a problem, a high-potency benzodiazepine medication such as clonazepam or lorazepam may be helpful. However, because these medications may be habit-forming, they are best prescribed short-term. Other types of sedative medications, such as zolpidem, are sometimes used instead.

Changes to the treatment plan may be needed at various times during the course of bipolar disorder to manage the illness most effectively. A psychiatrist should guide any changes in type or dose of medication. It is important to tell the psychiatrist about all other prescription drugs, over-the-counter medications, or natural supplements you may be taking. This is important because certain medications and supplements taken together may cause adverse reactions.

To reduce the chance of relapse or developing a new episode, it is important to stick to the treatment plan. Talk to your doctor if you have any concerns about the medications.

Thyroid Function

People with bipolar disorder often have abnormal thyroid gland function. Because too much or too little thyroid hormone alone can lead to mood and energy changes, it is important that thyroid levels are carefully monitored by a physician.

People with rapid cycling tend to have co-occurring thyroid problems and may need to take thyroid pills in addition to their medications for bipolar disorder. Lithium treatment may cause low thyroid levels in some people, resulting in the need for thyroid supplementation.

Medication Side Effects

Before starting a new medication for bipolar disorder, always talk with your psychiatrist or pharmacist about possible side effects. Depending on the medication, side effects may include weight gain, nausea, tremors, reduced sexual drive, anxiety, hair loss, movement problems, or dry mouth. Be sure to tell the doctor about all side effects during treatment. She may be able to change the dose or offer a different medication to relieve them. Your medication should not be changed or stopped without the psychiatrist’s guidance.

Psychosocial Treatment

As an addition to medication, psychosocial treatments—including certain forms of psychotherapy (or talk therapy)—are helpful in providing support, education, and guidance to patients and their families. Studies have shown that psychosocial interventions can lead to increased mood stability, fewer hospitalizations, and improved functioning in several areas. A licensed psychologist, social worker, or counselor typically provides these therapies and often works together with the psychiatrist to monitor progress. The number, frequency, and type of sessions should be based on the treatment needs of each person.

Psychosocial interventions commonly used for bipolar disorder are cognitive behavioral therapy, psychoeducation, family therapy, and a newer technique—interpersonal and social rhythm therapy. Researchers at the National Institute of Mental Health are studying how these interventions compare to one another when added to medication treatment for bipolar disorder.

Cognitive behavioral therapy helps people with bipolar disorder learn to change inappropriate or negative thought patterns and behaviors associated with the illness.

Psychoeducation involves teaching people with bipolar disorder about the illness and its treatment, and how to recognize signs of relapse so that early intervention can be sought before a full-blown episode occurs. Psychoeducation may also be helpful for family members.

Family therapy uses strategies to reduce the level of family distress that may either contribute to or result from the ill person’s symptoms.

Interpersonal and social rhythm therapy helps people with bipolar disorder both to improve interpersonal relationships and to regulate daily routines. Daily routines and sleep schedules may help protect against manic episodes.

As with medication, it is important to follow the treatment plan for any psychosocial intervention to achieve the greatest benefit.

Other Treatments

Electroconvulsive Therapy

In situations where medication, psychosocial treatment, and the combination of these interventions prove ineffective or work too slowly to relieve severe symptoms such as psychosis or suicidal thoughts, electroconvulsive therapy (ECT) may be considered. ECT may also be considered to treat acute episodes when medical conditions, including pregnancy, make the use of medications too risky. ECT is a highly effective treatment for severe depressive, manic, or mixed episodes. The possibility of long-lasting memory problems has been significantly reduced with modern ECT techniques. However, the potential benefits and risks of ECT and of available alternative interventions, should be carefully reviewed and discussed with individuals considering this treatment and, when appropriate, with family or friends.

Herbal and Natural Supplements

Herbal or natural supplements, such as St. John’s Wort, have not been well studied, and little is known about their effects on bipolar disorder. Because the FDA does not regulate their production, different brands of these supplements can contain different amounts of active ingredient.

Before trying herbal or natural supplements, it is important to discuss them with your doctor. There is evidence that St. John’s Wort can reduce the effectiveness of certain medications. In addition, like prescription antidepressants, St. John’s Wort may cause a switch into mania in some individuals with bipolar disorder, especially if no mood stabilizer is being taken.

Omega-3 fatty acids found in fish oil are being studied to determine their usefulness, alone and when added to conventional medications, for long-term treatment of bipolar disorder.

Even though episodes of mania and depression come and go, it is important to understand that bipolar disorder is a long-term illness that has no cure. Staying on treatment, even during periods without episodes, can help keep the disease under control and reduce the chance of having recurrent, worsening episodes.

People with bipolar disorder may need help to get help:

  • Often people with bipolar disorder do not realize how impaired they are, or they blame their problems on some cause other than mental illness.
  • A person with bipolar disorder may need strong encouragement from family and friends to seek treatment. Family physicians can play an important role in providing a referral to a mental-health professional.
  • Sometimes a family member or friend may need to take the person with bipolar disorder for proper mental health evaluation and treatment.
  • A person who is in the midst of a severe episode may need to be hospitalized for his or her own protection and for much-needed treatment. There may be times when the person must be hospitalized against his or her wishes.
  • Ongoing encouragement and support are needed after a person obtains treatment, because it may take a while to find the best treatment plan for the individual.
  • In some cases, individuals with bipolar disorder may agree, when the disorder is under good control, to a preferred course of action in the event of a future manic or depressive relapse.
  • Like other serious illnesses, bipolar disorder is also hard on spouses, family members, friends, and employers.
  • Family members of people with bipolar disorder often have to cope with the person’s serious behavioral problems, such as wild spending sprees during mania or extreme withdrawal from others during depression, and the lasting consequences of these behaviors.

Sources:

  • National Institute of Mental Health
  • Archives of General Psychiatry
  • Scientific American
  • Medicine
  • Goodwin FK & Jamison KR. Manic-depressive illness. New York: Oxford University Press, 1990.
  • Journal of the American Academy of Child and Adolescent Psychiatry
  • National Institute of Mental Health
  • Biological Psychiatry
  • Journal of Psychiatric Research
  • Postgraduate Medicine, 2000
  • Harvard Review of Psychiatry
  • Annals of Neurology
  • Journal of Clinical Psychiatry
  • American Journal of Psychiatry
  • U.S. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Mental Health Services, National Institutes of Health, National Institute of Mental Health
  • Journal of the American Medical Association
  • Clinical Psychology Review
  • Journal of Consulting and Clinical Psychology

Seasonal Affective Disorder

Tuesday, November 25th, 2008

Definition
Seasonal affective disorder (also called SAD) is a type of depression that follows the seasons. The most common type of SAD is called winter depression. It usually begins in late fall or early winter and normal mood returns in summer. A less common type of SAD, known as summer depression, usually begins in the late spring or early summer. SAD may be related to changes in the amount of daylight you get.

Seasonal affective disorder is estimated to affect 10 million Americans. Another 10 percent to 20 percent may have mild SAD. SAD is more common in women than in men. Illness typically begins around age 20. Some people experience symptoms severe enough to affect quality of life, and 6 percent require hospitalization. Many people with SAD report at least one close relative with a psychiatric disorder, most frequently a severe depressive disorder (55 percent) or alcohol abuse (34 percent). Although some children and teenagers get SAD, it usually doesn’t start in people younger than age 20. Yet when it does the syndrome is first suspected by parents and teachers. Risk decreases with age. SAD is more common the farther north you live.

Symptoms Not everyone with SAD has the same symptoms, but common symptoms of winter depression include the following:

  • Feelings of hopelessness and sadness
  • Thoughts of suicide
  • Hypersomnia or a tendency to oversleep
  • A change in appetite, especially a craving for sweet or starchy foods
  • Weight gain
  • A heavy feeling in the arms or legs
  • A drop in energy level
  • Decreased physical activity
  • Fatigue
  • Difficulty concentrating
  • Irritability
  • Increased sensitivity to social rejection
  • Avoidance of social situations

Symptoms of the summer SAD are:

  • Poor appetite
  • Weight loss
  • Insomnia
  • Agitation and anxiety

Either type of SAD may also include some of the symptoms that are present in other kinds of depression, such as feelings of guilt, a loss of interest or pleasure in activities previously enjoyed, ongoing feelings of hopelessness or helplessness, or physical problems such as headaches and stomachaches.

Symptoms of SAD tend to reoccur at about the same time every year. The changes in mood are not necessarily related to obvious seasonal stressors (like being regularly unemployed during the winter). Usually depression is mild or moderate. However, some people experience severe symptoms and 6 percent of SAD patients need hospitalization at some time in their lives.

Seasonal Affective Disorder can be misdiagnosed as hypothyroidyism, hypoglycemia, or a viral infection such as mononucleosis.

Causes The cause for SAD is unknown. One theory is that it is related to the amount of melatonin in the body, a hormone secreted by the pineal gland. The body is exposed to its secretions for a shorter period of time during summer because light suppresses it production. The long nights of winter extends the amount of time melatonin is released into the body, thus increasing symptoms. It is not clear how melatonin produces the symptoms reported. One possible explanation is that melatonin causes a drop in body temperature and lower body temperature is associated with sleep. This could indicate that it is related to the sleep-wake cycle and related to the hypersomnia and fatigue reported.

Treatment Because winter depression is probably caused by a reaction to a lack of sunlight, broad-band light therapy is frequently used. This therapy requires a light box or a light visor worn on the head like a cap. The individual either sits in front of the light box or wears light visor for a certain length of time each day. Generally, light therapy takes between 30 and 60 minutes each day throughout the fall and winter. The amount of time required varies with each individual. When light therapy is sufficient to reduce symptoms and to increase energy level, the individual continues to use it until enough daylight is available, typically in the springtime. Stopping light therapy too soon can result in a return of symptoms.

When used properly, light therapy seems to have very few side effects. Side effects include eyestrain, headache, fatigue, irritability and inability to sleep (when light therapy is used too late in the day). People with manic depressive disorders, skin that is sensitive to light, or medical conditions that make their eyes vulnerable to light damage may not be good candidates for light therapy.

When light therapy does not improve symptoms within a few days, then medication and, or, behavioral therapies should be introduced. In some cases, light therapy can be used in combination with anyone or all of these therapies.

Self-Care

  • Monitor your mood and energy level
  • Take advantage of available sunlight
  • Plan pleasurable activities for the winter season
  • Plan physical activities
  • Approach the winter season with a positive attitude
  • When symptoms develop seek help sooner rather than later

Sources:

  • American Psychiatric Association
  • Diagnostic and Statistical Manual of Mental Disorders, 4th Edition
  • The Cleveland Clinic: What is seasonal affective disorder?
  • National Alliance of Mental Illness
  • National Institute of Mental Health
  • U.S. Department of Health and Human Services; 2005
  • National Mental Health Association
  • American Family Physician
  • Substance Abuse and Mental Health Services Administration

Depressive Disorders

Tuesday, November 25th, 2008

Definition
A depressive disorder is an illness that involves the body, mood, and thoughts. When a person has a depressive disorder, it interferes with daily life, normal functioning, and causes pain for both the person with the disorder and those who care about him or her. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be willed or wished away. People with a depressive illness cannot merely “pull themselves together” and get better. Without treatment, symptoms can last for weeks, months, or years. Depression is a common but serious illness, and most people who experience it need treatment to get better. Appropriate treatment, however, can help most people who suffer from depression.

Depressive disorders come in different forms, just as is the case with other illnesses such as heart disease. Three of the most common types of depressive disorders are described here. However, within these types there are variations in the number of symptoms as well as their severity and persistence.

Major depression is manifested by a combination of symptoms (see symptom list) that interfere with the ability to work, study, sleep, eat, and enjoy once pleasurable activities. Such a disabling episode of depression may occur only once but more commonly occurs several times in a lifetime.

Dysthymic disorder, also called dysthymia, involves long-term (two years or longer) less severe symptoms that do not disable, but keep one from functioning normally or from feeling good. Many people with dysthymia also experience major depressive episodes at some time in their lives.

Some forms of depressive disorder exhibit slightly different characteristics than those described above, or they may develop under unique circumstances. However, not all scientists agree on how to characterize and define these forms of depression. They include:

Psychotic depression, which occurs when a severe depressive illness is accompanied by some form of psychosis, such as a break with reality, hallucinations, and delusions.

Postpartum depression, which is diagnosed if a new mother develops a major depressive episode within one month after delivery. It is estimated that 10 to 15 percent of women experience postpartum depression after giving birth.

Seasonal affective disorder (SAD), which is characterized by the onset of a depressive illness during the winter months, when there is less natural sunlight. The depression generally lifts during spring and summer. SAD may be effectively treated with light therapy, but nearly half of those with SAD do not respond to light therapy alone. Antidepressant medication and psychotherapy can reduce SAD symptoms, either alone or in combination with light therapy.

Bipolar disorder, also called manic-depressive illness is not as prevalent as major depression or dysthymia, and characterized by cycling mood changes: severe highs (mania) and lows (depression).

Symptoms Not everyone who is depressed or manic experiences every symptom. Some people experience a few symptoms, some many. Severity of symptoms varies with individuals and also varies over time.

  • Persistent sad, anxious, or empty mood
  • Feelings of hopelessness or pessimism
  • Feelings of guilt, worthlessness, or helplessness
  • Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
  • Decreased energy, fatigue, being “slowed down”
  • Difficulty concentrating, remembering, or making decisions
  • Insomnia, early morning awakening or oversleeping
  • Appetite and/or weight loss, or overeating and weight gain
  • Thoughts of death or suicide, suicide attempts
  • Restlessness, irritability
  • Persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders and chronic pain

Causes There is no single known cause of depression. Rather, it likely results from a combination of genetic, biochemical, environmental, and psychological factors.

Research indicates that depressive illnesses are disorders of the brain. Brain-imaging technologies, such as magnetic resonance imaging (MRI), have shown that the brains of people who have depression look different than those of people without depression. The parts of the brain responsible for regulating mood, thinking, sleep, appetite, and behavior appear to function abnormally. In addition, important neurotransmitters—chemicals that brain cells use to communicate—appear to be out of balance. But these images do not reveal why the depression has occurred.

Some types of depression tend to run in families, suggesting a genetic link. However, depression can occur in people without family histories of it as well. Genetics research indicates that risk for depression results from the influence of multiple genes acting together with environmental or other factors.

In addition, trauma, loss of a loved one, a difficult relationship, or any stressful situation may trigger a depressive episode. Subsequent depressive episodes may occur with or without an obvious trigger.

Depression in Women

Women experience depression about twice as often as men. Biological, life cycle, hormonal, and other factors unique to women may be linked to their higher depression rate. Researchers have shown that hormones directly affect brain chemistry that controls emotions and mood. Some women may be susceptible to a severe form of premenstrual syndrome called premenstrual dysphoric disorder (PMDD). Women affected by PMDD typically experience depression, anxiety, irritability, and mood swings the week before menstruation, in such a way that interferes with their normal functioning. Women with debilitating PMDD do not necessarily have unusual hormone changes, but they do have different responses to these changes. They may also have a history of other mood disorders and differences in brain chemistry that cause them to be more sensitive to menstruation-related hormone changes. Scientists are exploring how the cyclical rise and fall of estrogen and other hormones may affect the brain chemistry that is associated with depressive illness.

For example, women are particularly vulnerable to depression after giving birth, when hormonal and physical changes, along with the new responsibility of caring for a newborn, can be overwhelming. Many new mothers experience a brief episode of the “baby blues,” but some will develop postpartum depression, a much more serious condition that requires active treatment and emotional support for the new mother. Some studies suggest that women who experience postpartum depression have had prior depressive episodes. Treatment by a sympathetic physician and the family’s emotional support for the new mother are prime considerations in aiding her to recover her physical and mental well-being as well as her ability to care for and enjoy the infant.

Many women also face additional stresses of work and home responsibilities, single parenthood and caring for children and aging parents, abuse, poverty, and relationship strains. It remains unclear why some women faced with enormous challenges develop depression, while others with similar challenges do not.

Depression in Men

Researchers estimate that at least 6 million men in the United States suffer from a depressive disorder every year. Research and clinical evidence reveal that while both women and men can develop the standard symptoms of depression, they often experience depression differently and may have different ways of coping with the symptoms. Men may be more willing to acknowledge fatigue, irritability, loss of interest in work or hobbies, and sleep disturbances rather than feelings of sadness, worthlessness, and excessive guilt. Some researchers question whether the standard definition of depression and the diagnostic tests based upon it adequately capture the condition as it occurs in men.

Depression can also affect the physical health in men differently from women. One study shows that, although depression is associated with an increased risk of coronary heart disease in both men and women, only men suffer a high death rate.

Instead of acknowledging their feelings, asking for help, or seeking appropriate treatment, men may turn to alcohol or drugs when they are depressed, or become frustrated, discouraged, angry, irritable, and, sometimes, violently abusive. Some men deal with depression by throwing themselves compulsively into their work, attempting to hide their depression from themselves, family, and friends. Other men may respond to depression by engaging in reckless behavior, taking risks, and putting themselves in harm’s way.

More than four times as many men as women die by suicide in the United States, even though women make more suicide attempts during their lives. In light of the research indicating that suicide is often associated with depression, the alarming suicide rate among men may reflect the fact that many men with depression do not obtain adequate diagnosis and treatment that may be life saving.

Even if a man realizes that he is depressed, he may be less willing than a woman to seek help. Encouragement and support from concerned family members can make a difference. In the workplace, employee assistance professionals or work-site mental health programs can be of assistance in helping men understand and accept depression as a real illness that needs treatment.

Depression in the Elderly

Some people have the mistaken idea that it is normal for the elderly to feel depressed. On the contrary, older people feel satisfied with their lives. Sometimes, though, when depression develops, it may be dismissed as a normal part of aging. However, when older adults do have depression, it may be overlooked because seniors may show different, less obvious symptoms, and may be less inclined to experience or acknowledge feelings of sadness or grief.

In addition, older adults may have more medical conditions such as heart disease, stroke or cancer, which may cause depressive symptoms, or they may be taking medications with side effects that contribute to depression. Some older adults may experience what doctors call vascular depression, also called arteriosclerotic depression or subcortical ischemic depression. Vascular depression may result when blood vessels become less flexible and harden over time, becoming constricted. Such hardening of vessels prevents normal blood flow to the body’s organs, including the brain. Those with vascular depression may have, or be at risk for, a co-existing cardiovascular illness or stroke.

The majority of older adults with depression improve when they receive treatment with an antidepressant, psychotherapy, or a combination of both. Research has shown that medication alone and combination treatment are both effective in reducing the rate of depressive recurrences in older adults. Psychotherapy alone also can be effective in prolonging periods free of depression, especially for older adults with minor depression, and it is particularly useful for those who are unable or unwilling to take antidepressant medication.

Improved recognition and treatment of depression in late life will make those years more enjoyable and fulfilling for the depressed elderly person, the family, and caretakers.

Treatment Depression, even the most severe cases, is a highly treatable disorder. As with many illnesses, the earlier that treatment can begin, the more effective it is and the greater the likelihood that recurrence can be prevented. Appropriate treatment for depression starts with a physical examination by a physician. Certain medications, as well as some medical conditions such as viral infections or a thyroid disorder, can cause the same symptoms as depression, and the physician should rule out these possibilities through examination, interview and lab tests. If a physical cause for the depression is ruled out, a psychological evaluation that includes a mental status exam should be done either by the physician or by referral to a mental health professional.

He or she should discuss any family history of depression including their treatment, and get a complete history of symptoms, such as when they started, how long they have lasted, how severe they are, whether the patient had them before. And if so, whether the symptoms were treated and what treatment was given. The doctor should ask about alcohol and drug use, and if the patient has thoughts about death or suicide.

Once diagnosed, a person with depression can be treated with a number of methods. The most common treatments are medication and psychotherapy.

Medications

Antidepressants work to normalize naturally occurring brain chemicals called neurotransmitters, notably serotonin and norepinephrine. Other antidepressants work on the neurotransmitter dopamine.

The newest and most popular medications are called selective serotonin reuptake inhibitors (SSRIs). SSRIs include fluoxetine (Prozac), citalopram (Celexa), sertraline (Zoloft) and several others. Serotonin and norepinephrine reuptake inhibitors (SNRIs) are similar to SSRIs and include venlafaxine (Effexor) and duloxetine (Cymbalta). SSRIs and SNRIs are more popular than the older classes of antidepressants, such as tricyclics—named for their chemical structure—and monoamine oxidase inhibitors (MAOIs) because they tend to have fewer side effects. However, medications affect everyone differently so “no one-size-fits-all” approach to medication exists. Therefore, for some people, tricyclics or MAOIs may be the best choice.

People taking MAOIs must adhere to significant food and medicinal restrictions to avoid potentially serious interactions. They must avoid certain foods that contain high levels of the chemical tyramine, which is found in many cheeses, wines and pickles, and some medications including decongestants. MAOIs interact with tyramine in such a way that may cause a sharp increase in blood pressure, which could lead to a stroke. A doctor should give a patient taking an MAOI a complete list of prohibited foods, medicines and substances.

For all classes of antidepressants, patients must take regular doses for at least three to four weeks before they are likely to experience a full therapeutic effect. They should continue taking the medication for the time specified by their doctor, even if they are feeling better, in order to prevent a relapse of the depression. Medication should be stopped only under a doctor’s supervision. Some medications need to be gradually stopped to give the body time to adjust. Although antidepressants are not habit-forming or addictive, abruptly ending an antidepressant can cause withdrawal symptoms or lead to a relapse. Some individuals, such as those with chronic or recurrent depression, may need to stay on the medication indefinitely.

In addition, if one medication does not work, the doctor may switch to another medication and patients should be open to trying another. NIMH-funded research has shown that patients who did not improve after taking a first medication increased their chances of becoming symptom-free after they switched to a different medication or added another medication to their existing one.

Sometimes stimulants, anti-anxiety medications, or other medications are used in conjunction with an antidepressant, especially if the patient has a co-existing mental or physical disorder. However, neither anti-anxiety medications nor stimulants are effective against depression when taken alone, and both should be taken only under a doctor’s close supervision.

Medications of any kind—prescribed, over-the-counter or borrowed—should never be mixed without consulting the doctor. All health professionals who are working with the patient should be told of all the medications that are being taken. Some drugs, though safe when taken alone, can cause severe and dangerous side effects if taken with others. Some drugs, like alcohol or street drugs, may reduce the effectiveness of antidepressants and should be avoided.

Despite the relative safety and popularity of SSRIs and other antidepressants, some studies have suggested that they may have unintentional effects on some people, especially adolescents and young adults. Based on the FDA’s thorough review of published and unpublished controlled clinical trials of antidepressants of nearly 4,400 children and adolescents, the FDA was prompted, in 2005, to adopt a “black box” warning label on all antidepressant medications to alert the public about the potential increased risk of suicidal thinking or attempts in children and adolescents taking antidepressants. In 2007, the FDA proposed that makers of all antidepressant medications extend the warning to include young adults up through age 24. A “black box” warning is the most serious type of warning on prescription drug labeling.

Questions about any antidepressant prescribed, or problems that may be related to the medication, should be discussed with the doctor.

Side Effects

Antidepressants may cause mild and, usually, temporary side effects (sometimes referred to as adverse effects) in some people. Typically these are annoying, but not serious. However, any unusual reactions or side effects or those that interfere with functioning should be reported to the doctor immediately. The most common side effects of tricyclic antidepressants, and ways to deal with them, are:

  • Dry mouth—it is helpful to drink sips of water, chew sugarless gum and clean teeth daily.
  • Constipation—eat bran cereals, prunes, fruit and vegetables.
  • Bladder problems—emptying the bladder may be troublesome, and the urine stream may not be as strong as usual; the doctor should be notified if there is marked difficulty or pain.
  • Sexual problems—sexual functioning may change; if worrisome, discuss with the doctor.
  • Blurred vision—this will pass soon and will not usually necessitate new glasses.
  • Dizziness—rising from the bed or chair slowly is helpful.
  • Drowsiness as a daytime problem—this usually passes soon. A person feeling drowsy or sedated should not drive or operate heavy equipment. The more sedating antidepressants are generally taken at bedtime to help sleep and minimize daytime drowsiness.

The most common side effects associated with SSRIs and SNRIs include:

  • Headache—this usually goes away.
  • Nausea—this is also temporary, but even when it occurs, it is transient after each dose.
  • Nervousness and insomnia (trouble falling asleep or waking often during the night)—these may occur during the first few weeks; dosage reductions or time will usually resolve them.
  • Agitation (feeling jittery)—if this happens for the first time after the drug is taken and is more than transient, the doctor should be notified.
  • Sexual problems—the doctor should be consulted if the problem is persistent or worrisome.

Herbal Therapy

In the past few years, there has been much interest in the use of herbs in the treatment of both depression and anxiety. St. John’s Wort (Hypericum perforatum), an herb used extensively in the treatment of mild to moderate depression in Europe, has aroused interest in the United States. St. John’s Wort, an attractive bushy, low-growing plant covered with yellow flowers in summer, has been used for centuries in many folk and herbal remedies.

Because of the widespread interest in St. John’s Wort, the National Institutes of Health (NIH) conducted a three-year study, sponsored by three NIH components—the National Institute of Mental Health, the National Center for Complementary and Alternative Medicine, and the Office of Dietary Supplements. The study was designed to include 336 patients with major depression of moderate severity, randomly assigned to an eight-week trial. One third of patients received a uniform dose of St. John’s Wort; another third, sertraline, a selective serotonin reuptake inhibitor (SSRI) commonly prescribed for depression; and the final third, a placebo (a pill that looks exactly like the SSRI and St. John’s Wort, but has no active ingredients). The trial found that St. John’s wort was no more effective than the placebo in treating major depression.

A late 2008 German study reviewed and analyzed previous studies on St. John’s Wort in the treatment of mild or minor depression. Their results indicated that the herbal remedy was effective and study participants experienced fewer side effects. Yet the researchers issued some caveats regarding their findings. First, the St. John’s Wort that is available on the market varies widely so their results are only applicable to the preparations tested. Secondly, they cautioned against using the remedy without medical advice because St. John’s Wort can affect the effectiveness of other drugs.

In February 2000, the Food and Drug Administration had issued a Public Health Advisory, stating that St. John’s Wort appears to interfere with certain drugs prescribed to treat conditions such as AIDS, heart disease, depression, seizures, certain cancers and organ transplant rejection. The herb also may interfere with the effectiveness of oral contraceptives. Because of these potential interactions, patients should always consult with their doctors before taking any herbal supplement.

Psychotherapies

Many forms of psychotherapy, including some short-term (10- to 20-week) and other regimens are longer-term, depending on the needs of the individual. Two main types of psychotherapies—cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT)—have been shown to be effective in treating depression. By teaching new ways of thinking and behaving, CBT helps people change negative styles of thinking and behaving that may contribute to their depression. IPT helps people understand and work through troubled personal relationships that may cause their depression or make it worse.

For mild to moderate depression, psychotherapy may be the best treatment option. However, for major depression or for certain people, psychotherapy may not be enough. Studies have indicated that for adolescents, a combination of medication and psychotherapy may be the most effective approach to treating major depression and reducing the likelihood for recurrence. Similarly, a study examining depression treatment among older adults found that patients who responded to initial treatment of medication and IPT were less likely to have recurring depression if they continued their combination treatment for at least two years.

Electroconvulsive therapy (ECT) is useful, particularly for individuals whose depression is severe or life threatening, or for those who cannot take antidepressant medication. ECT often is effective in cases where antidepressant medications do not provide sufficient relief of symptoms. In recent years, ECT has been much improved. A muscle relaxant is given before treatment, which is done under brief anesthesia. Electrodes are placed at precise locations on the head to deliver electrical impulses. The stimulation causes a brief (about 30 seconds) seizure within the brain. The person receiving ECT does not consciously experience the electrical stimulus. For full therapeutic benefit, at least several sessions of ECT, typically given at the rate of three per week, are required.

How to Help Yourself If You Are Depressed

Depressive disorders can make a person feel exhausted, worthless, helpless and hopeless. Such negative thoughts and feelings make some people feel like giving up. It is important to realize that these negative views are part of the depression and typically do not reflect actual circumstances. Negative thinking fades as treatment begins to take effect. In the meantime:

  • Set realistic goals in light of the depression and assume a reasonable amount of responsibility.
  • Break large tasks into small ones, set some priorities and do what you can, as you can.
  • Try to be with other people and to confide in someone; it is usually better than being alone and secretive.
  • Participate in activities that may make you feel better.
  • Mild exercise, going to a movie or a ball game, or participating in religious, social or other activities may also help.
  • Expect your mood to improve gradually, not immediately; feeling better takes time.
  • It is advisable to postpone important decisions until the depression has lifted. Before deciding to make a significant transition—change jobs, get married or divorce—discuss it with others who know you well and have a more objective view of your situation.
  • People rarely “snap out of” a depression. But they can feel a little better day by day.
  • Remember, positive thinking will replace the negative thinking that is part of the depression, and this negative thinking will disappear as your depression responds to treatment.
  • Let your family and friends help you.

How Family and Friends Can Help the Depressed Person

If you know someone who is depressed, it affects you too. The most important thing anyone can do for the depressed person is to help him or her get an appropriate diagnosis and treatment. You may need to make an appointment on behalf of your friend or relative and go with her to see the doctor. Encourage him to stay in treatment, or to seek different treatment if no improvement occurs after six to eight weeks.

The second most important thing is to offer emotional support. This involves understanding, patience, affection and encouragement. Engage the depressed person in conversation and listen carefully. Do not disparage feelings expressed, but point out realities and offer hope. Do not ignore remarks about suicide. Report them to the depressed person’s therapist. Invite the depressed person for walks, outings, to the movies and other activities. Keep trying if he declines, but don’t push her to take on too much too soon. Although diversions and company are needed, too many demands may increase feelings of failure. Remind your friend or relative that with time and treatment, the depression will lift.

Sources:

  • Medscape Women’s Health Depression
  • National Health and Nutrition Examination Survey
  • Archives of Internal Medicine
  • Psychopharmacology Bulletin
  • Journal of the American Medical Association
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  • Tsuang MT, Bar JL, Stone WS, Faraone SV. Gene-environment interactions in mental disorders. World Psychiatry, 2004 June; 3(2): 73-83.
  • Schmidt PJ, Nieman LK, Danaceau MA, Adams LF, Rubinow DR. Differential behavioral effects of gonadal steroids in women with and in those without premenstrual syndrome. New England Journal of Medicine. 1998 Jan 22; 338(4): 209-216
  • Dreher JC, Schmidt PJ, Kohn P, Furman D, Rubinow D, Berman KF. Menstrual cycle phase modulates reward-related neural function in women. Proceedings of the National Academy of Sciences. 2007 Feb 13; 104(7): 2465-2470.
  • Pollack W. Mourning, melancholia, and masculinity: recognizing and treating depression in men. In: Pollack W, Levant R, eds. New Psychotherapy for Men. New York: Wiley, 1998; 147 66.
  • Cochran SV, Rabinowitz FE. Men and depression: clinical and empirical perspectives. San Diego: Academic Press, 2000.
  • Gallo JJ, Rabins PV. Depression without sadness: alternative presentations of depression in late life. American Family Physician, 1999; 60(3): 820-826.
  • Reynolds CF III, Dew MA, Pollock BG, Mulsant BH, Frank E, Miller MD, Houck PR, Mazumdar S, Butters MA, Stack JA, Schlernitzauer MA, Whyte EM, Gildengers A, Karp J, Lenze E, Szanto K, Bensasi S, Kupfer DJ. Maintenance treatment of major depression in old age. New England Journal of Medicine, 2006 Mar 16; 354(11): 1130-1138.
  • Rush JA, Trivedi MH, Wisniewski SR, Stewart JW, Nierenberg AA, Thase ME, Ritz L, Biggs MM, Warden D, Luther JF, Shores-Wilson K, Niederehe G, Fava M. Bupropion-SR, Sertraline, or Venlafaxine-XR after failure of SSRIs for depression. New England Journal of Medicine, 2006 Mar 23; 354(12): 1231-1242.
  • Trivedi MH, Fava M, Wisniewski SR, Thase ME, Quitkin F, Warden D, Ritz L, Nierenberg AA, Lebowitz BD, Biggs MM, Luther JF, Shores-Wilson K, Rush JA. Medication augmentation after the failure of SSRIs for depression. New England Journal of Medicine, 2006 Mar 23; 354(12): 1243-1252.

Bereavement

Tuesday, September 2nd, 2008

Definition
Bereavement means to be deprived of someone by death. The death of someone you love is one of the greatest losses that can occur. However, feelings of bereavement can also accompany other losses, such as the loss of your health or the health of someone you care about—or the end of an important relationship, through divorce, for example. Grief is a normal, healthy response to loss.

Everyone feels grief in their own way, but there are certain stages to the process of mourning. It starts with recognizing a loss and continues until a person eventually accepts that loss. People’s responses to grief will vary depending upon the circumstances of the death.

For example, if the person who died had a chronic illness, the death may have been expected. The end of the person’s suffering might even have come as a relief. If the death was accidental or violent, coming to a stage of acceptance could take longer.

Symptoms A wide and confusing range of emotions may be experienced after a loss. There can be five stages of grief. These reactions might not occur in a specific order, and can (at times) occur together. Not everyone experiences all of these emotions:

  • Denial, disbelief, numbness
  • Anger, blame
  • Bargaining (for instance, “If I am cured of this cancer, I will never smoke again”)
  • Depressed mood, sadness, and crying
  • Acceptance, coming to terms

People who are grieving will often report crying spells, some trouble sleeping, and lack of productivity at work. At this time, you may find it hard to accept that the loss has actually occurred.

Once the initial shock has worn off, denial of the loss can often be replaced by feelings of anger. The anger may be directed toward doctors and nurses, God, other loved ones, yourself, or even the person who has died. You may experience feelings of guilt with sentiments such as “I should have… “, “I could have… “, or “I wish I had… ” Such thoughts are common. Your emotions may be very intense and you may have mood swings. These are all normal reactions to loss.

Each type of loss means the person has had something taken away. Grief may be experienced as a mental, physical, social, or emotional reaction. Mental reactions can include anger, guilt, anxiety, sadness, and despair. Physical reactions can include sleeping problems, changes in appetite, physical problems, or illness. Social reactions can include feelings about seeing family or friends or returning to work. As with bereavement, grief processes depend on the relationship with the person who died, the situation surrounding the death, and the person’s attachment to the person who died. Grief may be described as the presence of physical problems, constant thoughts of the person who died, guilt, hostility, and a change in the way one normally acts.

Mourning is the process by which people adapt to a loss; mourning is also influenced by cultural customs, rituals, and society’s rules for coping.

Bereavement is the period after a loss during which grief is experienced and mourning occurs. The time spent in a period of bereavement depends on how attached the person was to the person who died, and how much time was spent anticipating the loss.

If you feel that you are not coping with bereavement, it is important to seek help. Although it may seem easier to bury your pain than to face it, unresolved grief can cause long-term physical or emotional illness.

Causes Your reaction to loss will, in part, be influenced by the circumstances surrounding it. The death of a loved one is always difficult, particularly when it is sudden or accidental. Your relationship to the person who has died will greatly influence your reaction to the loss.

A Spouse’s Death

The loss of a husband or wife is particularly hard. The surviving spouse will usually have to deal with a multitude of decisions regarding funeral arrangements, finances, and other legalities at a time when they may feel least able to deal with such matters. The bereaved spouse may also have to explain the death to children and help them through their grief. In addition to the severe emotional trauma, the death may lead to financial problems if the deceased spouse was the family’s main source of income. Returning to the job market (or entering it for the first time) can be one of the most challenging tasks for the recently bereaved spouse. When searching for a job, look for ways to capitalize on the skills you have developed over the years.

A Child’s Death

Regardless of the cause of death, or the age of the child, this is an emotionally devastating event that overwhelms a parent. A child’s death arouses an overwhelming sense of injustice—for lost potential, unfulfilled dreams, and senseless suffering. Parents may feel responsible for the child’s death, no matter how irrational that may seem. Parents may also feel that they have lost a vital part of their own identity.

A Parent’s Death

No matter what age you are—young or old, single or with a family of your own—you will still be deeply affected by the death of your mother or father. When your mom or dad dies, it may be one of the most emotional losses you’ll experience in life. It is only natural to feel consumed by a combination of pain, fear, and deep sadness at the loss of such a significant influence in your life.

The specifics of how you grieve will depend on a number of personal factors, including your relationship with your parent, age, gender, religious beliefs, previous experience with death, and whether or not you believe it was time for your parent to die.

When you lose a parent, you may also lose a lifelong friend, counselor, and adviser. Therefore, you may suddenly feel very much alone, even if you have the support of other family and friends. Even the loss of your parent’s home as a natural place for family gatherings can add to the grief you experience.

After the initial shock fades, you will experience what is called secondary loss. This is when you may begin to think of all the upcoming experiences that your parent will not be there to share in. Things like career accomplishments, watching your own children grow, and other milestones. If you are older, the death of a parent may even bring up issues of your own mortality.

Allowing yourself to grieve for the loss of your parent will help you to say goodbye and loosen the emotional bonds to a loved one who has been a special part of your life.

A Loss Due To Suicide

For every suicide it is claimed that on average six people suffer intense grief. Those affected include parents, partners, children, siblings, relatives, friends, coworkers, and clinicians. Coping with bereavement through suicide can be more difficult than dealing with other losses because of the feelings of stigmatization, shame, guilt, and rejection that are often experienced. The stigma that still attaches to deaths by suicide in many cultures can increase the bereaved person’s sense of isolation and vulnerability.

A Pet’s Death

The death of a pet will often mean the loss of a cherished family member and can trigger great sorrow. People love their pets and consider them members of their family. Caregivers celebrate their pets’ birthdays, confide in their animals, and carry pictures of them in their wallets. So when your beloved pet dies, it’s not unusual to feel overwhelmed by the intensity of your sorrow. Animals provide companionship, acceptance, emotional support, and unconditional love during the time they share with you. Other people may find it hard to understand such a reaction to what they may see as the loss of “just an animal,” and they may, therefore, be less understanding of your grief. However, your loss is significant and you should give yourself permission to mourn the passing of your beloved pet.

Anticipatory Grief

Anticipatory grief is the normal mourning that occurs when a patient or family is expecting a death. Anticipatory grief has many of the same symptoms as those experienced after a death has occurred.

Anticipatory grief includes depression, extreme concern for the dying person, preparing for the death, and adjusting to changes caused by the death. It can give the family time to get used to the reality of the impending loss. People are able to complete “unfinished business” with the dying person (for example, saying “good-bye,” “I love you,” or “I forgive you”).

Anticipatory grief may not always occur. A person does not necessarily feel the same kind of grief before a death occurs as the grief felt after a death. There is no set amount of grief that a person will feel. Grief experienced before a death does not make the grief after that death easier or shorter in duration.

Some people believe that anticipatory grief is rare. To accept a loved one’s death while he or she is still alive may leave the mourner feeling as if the dying patient has been abandoned. Furthermore, expecting the loss can make the attachment to the dying person stronger. Although anticipatory grief may help the family, witnessing the grief of family and friends can be very hard for the dying person who can become withdrawn as a result.

Some grief reactions are not considered “normal.” For example, persistent and intrusive feelings of guilt in the survivor (or thoughts that he or she should have died along with the deceased) are more characteristic of depression than normal bereavement. Depression in bereavement can be successfully treated.

Other losses occurring in later life may precipitate grief or depression. Retirement, loss of income, deteriorating physical health, and having to give up driving are just some of the more common occurrences that might cause grief reactions in older people.

Treatment Grief is a powerful emotion. It is painful and exhausting. Therefore, it sometimes seems easier to avoid confronting these feelings. However, this approach is not a viable long-term solution. Buried grief can manifest itself later as physical or emotional illness. Working through your sorrow and allowing yourself to express your feelings will help you to heal.

“Grief work” includes the stages a mourner needs to complete before resuming daily life. These processes include separating from the person who died, readjusting to a world without him or her, and forming new relationships. To separate from the person who died, a person must find another way to redirect the emotional energy that was given to the loved one. This does not mean the deceased was not loved or should be forgotten, but that the mourner needs to turn to others for emotional satisfaction. The mourner’s roles, identity, and skills may need to change to readjust to living in a world without the person who died. The bereaved needs to redirect the emotional energy that was once given to the deceased to other people or activities.

It is important not to neglect yourself while grieving. Try to eat regular, healthy meals. If meal preparation is too difficult, try eating several smaller snacks throughout the day.

Grieving is extremely tiring, both physically and emotionally. The grief one is feeling is not just for the person who died, but also for the unfulfilled wishes and plans with the person. Death often reminds people of past losses or separations. Mourning may be described as having the following three phases:

  • The urge to bring back the person who died
  • Disorganization and sadness
  • Reorganization

Depression shares common features with grief, but can completely take over the way you think and feel.

Symptoms of depression include:

  • A sad or “empty” mood that will not go away or lighten
  • Persistent feelings of hopelessness or worthlessness
  • A negative preoccupation with self

Depression in older people has been linked to death from suicide, heart attack, and other causes. Much can be done to ameliorate severe symptoms through formal treatment or through support-group participation. If you feel that you or someone you know is having difficulty in coping with their loss, seek professional help. A family physician can often help, or grief counseling or therapy may be appropriate.

Grief counseling helps mourners with normal grief reactions work through the tasks of grieving. Grief counseling can be provided by professionally trained people or in self-help groups where bereaved people help each other. All of these services may be available in individual or group settings.

The goals of grief counseling include:

  • Describing normal grieving and encouraging the bereaved to accept the loss by talking about it
  • Helping the bereaved to identify and express feelings related to the loss (for example, anger, guilt, anxiety, helplessness, and sadness)
  • Helping the bereaved to separate emotionally from the deceased, as well as to make decisions and live alone
  • Helping the bereaved to understand his or her methods of coping
  • Describing normal grieving and the differences in grieving among individuals
  • Providing continuous support
  • Providing support at important times, such as birthdays and anniversaries
  • Identifying coping problems the bereaved may have, and making recommendations for professional grief therapy, if necessary

Grief therapy is used with people who have more serious grief reactions. The goal of grief therapy is to identify and solve problems the mourner may have in separating from the person who died. When separation difficulties occur, they may appear as physical or behavioral problems, delayed or extreme mourning, conflicted or extended grief, or unexpected mourning.

In grief therapy, the mourner talks about the deceased and tries to recognize whether he or she is experiencing an expected amount of emotion about the death. Grief therapy may allow the mourner to see that anger, guilt, or other negative or uncomfortable feelings can exist at the same time as more positive feelings about the person who died.

Humans tend to make strong bonds of affection or attachment with others. When these bonds are broken, as in death, a strong emotional reaction occurs. After a loss, a person must accomplish certain tasks to complete the process of grief. These basic tasks of mourning include accepting that the loss happened, living with and feeling the physical and emotional pain of grief, adjusting to life without the loved one, and emotionally separating from the loved one and going on without him. It is important that these tasks are completed before mourning can end.

In grief therapy six tasks can be used to help a mourner work through her grief:

  1. Develop the ability to experience, express, and adjust to painful grief-related changes
  2. Find effective ways to cope
  3. Establish a continuing relationship with the person who died
  4. Stay healthy and keep functioning
  5. Reestablish relationships, and understand that others may have difficulty empathizing with the grief he is experiencing
  6. Develop a healthy image of herself and the world

Complications in grief may come about due to unresolved grief from earlier losses. The grief for these earlier losses must be managed to handle the current grief. Grief therapy includes dealing with blockages to the mourning process, identifying any unfinished business with the deceased and identifying other losses that result from the death. The bereaved must see that the loss is final and to picture life after the mourning period.

Grief therapy may be available as individual or group therapy. A contract is set up with the individual that establishes the time limit of the therapy, the fees, the goals, and the focus of the therapy.

Complicated Grief

Complicated grief reactions require more complex therapies than uncomplicated grief reactions. Adjustment disorders (especially depressed and anxious mood or disturbed emotions and behavior), major depression, substance abuse, and even post-traumatic stress disorder are some of the common problems of complicated bereavement. Complicated grief is identified by the extended duration of the symptoms, the disruption to daily life caused by the symptoms or by the intensity of the symptoms (for example, intense suicidal thoughts or acts).

Complicated or unresolved grief may appear as a complete absence of grief and mourning, an ongoing inability to experience normal grief reactions, delayed grief, conflicted grief, or chronic grief. Factors that contribute to the chance that one may experience complicated grief include the suddenness of the death, the gender of the person in mourning, and the relationship to the deceased (for example, an intense, extremely close or very contradictory relationship).

Grief reactions that turn into major depression require treatment. Someone who avoids any reminders of the person who died, who constantly thinks or dreams about the person who died, or who gets scared and panics easily at any reminders of the deceased may be suffering from post-traumatic stress disorder. Substance abuse may occur, frequently in an attempt to avoid painful feelings about the loss and consequent symptoms (such as sleeplessness), and this should also be treated.

Children and Grief

In the past, children were thought to be miniature adults and were expected to behave as adults. It is now understood that there are differences in the ways in which children and adults mourn.

Unlike adults, bereaved children do not experience continual and intense emotional and behavioral grief reactions. Children may seem to show grief only occasionally and briefly, but in reality a child’s grief usually lasts longer than that of an adult. This may be explained by the fact that a child’s ability to experience intense emotions is limited. Mourning in children may need to be addressed again and again as the child gets older. Since bereavement is a process that continues over time, children will think about the loss repeatedly, especially during important times in their life, such as going to camp, graduating from school, getting married, or giving birth to their own children.

A child’s grief may be influenced by her age, personality, developmental stage, earlier experiences with death, and her relationship with the deceased. The surroundings, cause of death, family members’ ability to communicate with one another and to continue as a family after the death can also affect grief. Factors that may influence grief include the child’s ongoing need for care, the child’s opportunity to share his feelings and memories, the parent’s ability to cope with stress, and the child’s steady relationships with other adults.

Children do not react to loss in the same ways as adults. Grieving children may not show their feelings as openly as adults. Grieving children may not withdraw and dwell on the person who died, but instead may throw themselves into activities (for example, they may be sad one minute and playful the next). Often families think the child doesn’t really understand or has gotten over the death. Neither is true; children’s minds protect them from what is too powerful for them to handle. Children’s grieving periods are shortened because they cannot think through their thoughts and feelings like adults. Also, children have trouble putting their feelings about grief into words. Instead, his behavior speaks for the child. Strong feelings of anger and fears of abandonment or death may show up in the behavior of grieving children. Children often play death games as a way of working out their feelings and anxieties. These games are familiar to the children and provide safe opportunities to express their feelings.

Children’s Grief and Developmental Stages

Children at different stages of development have different understandings of death and the events near death.

Infants

Infants do not recognize death, but feelings of loss and separation are part of developing an awareness of death. Children who have been separated from their mother may be sluggish, quiet, unresponsive to smiling or cooing, undergo physical changes (for example, weight loss), be less active, and sleep less.

Age 2-3 years

Children at this age often confuse death with sleep and may experience anxiety as early as age 3. They may stop talking and appear to feel overall distress.

Age 3-6 years

At this age children see death as a kind of sleep; the person is alive, but only in a limited way. The child cannot fully separate death from life. Children may think that the person is still living, even though she might have been buried, and ask questions about the deceased (for example, how does the deceased eat, go to the toilet, breathe, or play?). Young children know that death occurs physically, but think it is temporary, reversible, and not final. The child’s concept of death may involve magical thinking. For example, the child may think that his or her thoughts can cause another person to become sick or die. Grieving children under 5 may have trouble eating, sleeping, and controlling bladder and bowel functions.

Age 6-9 years

Children at this age are commonly curious about death, and may ask questions about what happens to one’s body when it dies. Death is thought of as a person or spirit separate from the person who was alive, such as a skeleton, ghost, angel of death, or bogeyman. They may see death as final and frightening but as something that happens mostly to old people (and not to themselves). Grieving children can become afraid of school, have learning problems, develop antisocial or aggressive behaviors, become overly concerned about their own health (for example, developing symptoms of imaginary illness), or withdraw from others. Or, children this age can become too attached and clinging. Boys usually become more aggressive and destructive (for example, acting out in school), instead of openly showing their sadness. When a parent dies, children may feel abandoned by both their deceased parent and their surviving parent because the surviving parent is grieving and is unable to emotionally support the child.

Ages 9 and older

By the time a child is 9 years old, death is known to be unavoidable and is not seen as a punishment. By the time a child is 12 years old, death is seen as final and something that happens to everyone.

Treatment—Child Specific

A child’s grieving process may be made easier by being open and honest with the child about death. Not talking about death indicates that the subject is taboo and does not help a child to cope with loss. Use clear, direct language. Explanations should be simple and straightforward. Euphemisms such as “She passed away” or “We lost him” are best avoided, as they can confuse and alarm children. Each child should be told the truth, using as much detail as he or she is able to understand. Listen to any questions the child may have and try to answer them as fully as possible. Children often need to be reassured about their own security (they often worry that they, or a surviving parent, will also die).

If you are planning a memorial ceremony, try to include the child in the arrangements and in the ceremony itself. These events help children (and adults) remember loved ones. Children should not be forced to be involved in funerals or memorials, but they should be encouraged to take part in those portions of the events with which they feel most comfortable. If the child wants to attend the funeral, wake or memorial service, she should be given a full explanation of what to expect in advance. Try to encourage them to express their feelings. The surviving parent may be too incapacitated by his own grief to give the child full attention. Therefore, support from a familiar adult or family member can be extremely helpful.

Sources:

  • AARP
  • National Cancer Institute
  • National Institutes of Health-Bethesda
  • National Institutes of Health-National Library of Medicine
  • Canadian Mental Health Association
  • Mental Health Association
  • Worden JW: Grief Counseling and Grief Therapy. New York: Springer Publishing Company
  • Shuchter SR and Zisook S. Treatment of spousal bereavement: a multidimensional approach. Psychiatric Annals 16 (5): 295-305.
  • Corr CA, Nabe CM, Corr DM: Death and Dying, Life and Living. 2nd ed. Pacific Grove, Calif: Brooks/Cole Publishing Company
  • Humane Society of the United States
  • National Funeral Directors Association

Adult ADHD

Saturday, August 2nd, 2008

Definition
Attention-deficit/hyperactivity disorder is a neurobehavioral disorder characterized by a combination of inattentiveness, distractibility, hyperactivity, and impulsive behavior. AD/HD appears early in life. It is estimated that 3 percent to 7 percent of school-age children are diagnosed with AD/HD; boys are diagnosed more often than girls. Untreated AD/HD has been shown to have long-term adverse affects on academic performance, vocational success, and social-emotional development. AD/HD children have difficulty sitting still and paying attention in class and do not do well at school, even when they have normal or above-normal intelligence. They engage in a broad array of disruptive behaviors and experience peer rejection. As they grow older, children with untreated AD/HD are more prone to drug abuse, antisocial behavior, and injuries of all sorts. More than half the children diagnosed with AD/HD continue to have symptoms during their adolescent years and into adulthood.

Symptoms Diagnosing an adult with AD/HD is not easy. Many times, when a child is diagnosed with the disorder, a parent will recognize that he or she has many of the same symptoms the child has and, for the first time, will begin to understand some of the traits that have given him or her trouble for years—distractibility, impulsivity, restlessness. Other adults will seek professional help for depression or anxiety and will find out that the root cause of some of their emotional problems is AD/HD. They may have a history of school failures, problems at work, or frequent automobile accidents.

To be diagnosed with AD/HD, an adult must have childhood-onset, persistent, and current symptoms. The accuracy of the diagnosis of adult AD/HD is of utmost importance and should be made by a clinician with expertise in the area of attention dysfunction. For an accurate diagnosis, a history of the patient’s childhood behavior, together with an interview with his life partner, a parent, close friend, or other close associate, will be needed. A physical examination and psychological tests should also be given. Comorbidity with other conditions may exist such as specific learning disabilities, anxiety, or affective disorders.

A correct diagnosis of AD/HD can bring a sense of relief. The individual has brought into adulthood many negative perceptions of himself that may have led to low esteem. Now he can begin to understand why he has some of his problems and can begin to face them. This may mean, not only treatment for AD/HD but also psychotherapy that can help him cope with the anger he feels about the failure to diagnose the disorder when he was younger.

Causes Health professionals are still unsure about what causes AD/HD. It may be a genetically determined disorder, as attention disorders often run in families. Studies indicate that 25 percent of close relatives in the families of AD/HD children also have AD/HD, whereas the rate is about 5 percent in the general population. Many studies of twins now show that a strong genetic influence exists in the disorder.

Recent studies show that AD/HD is caused by neurobiological dysfunction. Scientists using neuroimaging and brain scanning tools for studying the brain have demonstrated a link between a person’s ability to maintain attention and the level of activity in the brain. For example, scientists have found differences between the frontal lobes of individuals who have AD/HD and those who do not.

Current research is exploring the structure of the brain to determine if there are differences that might indicate a physical basis for attention-deficit/hyperactivity disorder.

There is correlating evidence between the use of cigarettes and alcohol during pregnancy and the risk for developing AD/HD in the unborn child. These substances may endanger the fetus’ developing brain. It is best to refrain from smoking, alcohol use, and use of other drugs during pregnancy, as they may distort developing nerve cells and lead to AD/HD.

Toxins in the environment may also disrupt brain development or brain processes, which may lead to AD/HD. Lead is one such possible toxin. It is found in dust, soil, and flaking paint in areas where leaded gasoline or paint were once used. It is also present in some older water pipes.

There is, however, little compelling evidence that AD/HD stems from the home environment. Researchers report that not all children from unstable or dysfunctional homes have AD/HD, and not all children with AD/HD come from dysfunctional families. Scientists have also found no real evidence that head injury, undetectable damage to the brain, early infection, or complications at birth cause AD/HD.

Typically, adults with AD/HD are unaware that they have this disorder—they often just feel that it’s impossible to get organized, to stick to a job, to keep an appointment. The everyday tasks of getting up, getting dressed and ready for the day’s work, getting to work on time, and being productive on the job can be major challenges for the AD/HD adult.

Treatment When adults take a medication for AD/HD, they often start with a stimulant medication. The stimulant medications affect the regulation of two neurotransmitters, norepinephrine and dopamine. The newest medication approved for AD/HD by the FDA, atomoxetine (Strattera®), has been tested in controlled studies in both children and adults and has been found to be effective.

Antidepressants are considered a second choice for treatment of adults with AD/HD. The older antidepressants, the tricyclics, are sometimes used because they, like the stimulants, affect norepinephrine and dopamine. Venlafaxine (Effexor®), a newer antidepressant, is also used for its effect on norepinephrine. Bupropion (Wellbutrin®), an antidepressant with an indirect effect on the neurotransmitter dopamine, has been useful in clinical trials on the treatment of AD/HD in both children and adults. It has the added attraction of being useful in reducing cigarette smoking.

In prescribing for an adult, special considerations are made. The adult may need less of the medication for his weight, or at its regular dosage its effect may last longer in an adult. The adult may take other medications for physical problems, such as diabetes or high blood pressure; often the adult is also taking a medication for anxiety or depression. All of these variables must be taken into account before a medication is prescribed.

Although medication gives needed support, the individual must succeed on his own. To help in this struggle, both AD/HD education and individual psychotherapy can be helpful. The therapist can encourage the AD/HD patient to adjust to changes brought into his life by treatment—the perceived loss of impulsivity and love of risk-taking, the new sensation of thinking before acting. As the patient begins to have small successes in his new ability to bring organization out of the complexities of his or her life, he or she can begin to appreciate the characteristics of AD/HD that are positive—boundless energy, warmth, and enthusiasm.

Treatment plans for adult AD/HD may include:

  1. Consultation with appropriate medical professionals
  2. Education about AD/HD
  3. Medication
  4. Support groups
  5. Psychotherapy for help change a longstanding poor self-image
  6. Coaching in organizational skills
  7. Vocational/educational counseling
  8. Appropriate accommodations for work and school (NIMH, 2006)

Sources:

  • American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision
  • Barkley R.A. (2000). Taking Charge of AD/HD. New York: The Guilford Press, p. 21.
  • Biederman J, Faraone SV, Keenan K, Knee D, Tsuang MF. (1990) Family-genetic and psychosocial risk factors in DSM-III attention deficit disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 29(4): 526-533.
  • Consensus Development Panel (CDP) (1982). Defined Diets and Childhood Hyperactivity. National Institutes of Health Consensus Development Conference Summary, Volume 4(3).
  • Faraone SV, Biederman J. (1998) Neurobiology of attention-deficit hyperactivity disorder. Biological Psychiatry, 44, 951-958.
  • Harvard Mental Health Letter (2002). Attention Deficit Disorder in Adults. Vol. 19:5, 3-6.
  • The MTA Cooperative Group. A 14-month randomized clinical trial of treatment strategies for attention-deficit hyperactivity disorder (AD/HD) (1999). Archives of General Psychiatry, 56:1073-1086.
  • National Institute of Mental Health (2006). Attention-Deficit/Hyperactivity Disorder. Bethesda (MD): National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services. http://www.nimh.nih.gov/publicat/AD/HD.cfm#teen
  • National Institutes of Health - National Library of Medicine - MedlinePlus, 2007. Attention deficit hyperactivity disorder (AD/HD). http://www.nlm.nih.gov/medlineplus/ency/article/001551.htm
  • US Department of Justice (USDOJ) (2006). A Guide to Disability Rights Laws. Civil Rights Division: Disability Rights Section http://www.usdoj.gov/crt/ada/cguide.htm#anchor62335
  • U.S. Department of Transportation, National Highway Traffic Safety Administration. State Legislative Fact Sheet, April 2002.
  • Wilens TC, Faraone, SV, Biederman J, Gunawardene S. (2003). Does stimulant therapy of attention-deficit/hyperactivity disorder beget later substance abuse? A meta-analytic review of the literature. Pediatrics, 111:1:179-185.
  • Wilens TE, Biederman J, Spencer TJ. Attention (2002). deficit/hyperactivity disorder across the lifespan. Annual Review of Medicine, 53:113-131.

Sadness Is Not Depression

Monday, April 28th, 2008

We all feel sad sometimes. Sadness is a normal emotion that can make life more interesting. Much art and poetry is inspired by sadness and melancholy. Sadness almost always accompanies loss. When we say goodbye to a loved one we usually feel sad. The sadness is even deeper if a close relationship has ended or a loved one has died.

Sadness also helps us appreciate happiness. When our mood eventually changes from sadness toward happiness the sense of contrast adds to the enjoyment of the mood.

Here are some ways to experience normal sadness in a healthy way and to allow this emotion to enrich your life:

  • Allow yourself to be sad. Denying such feelings may force them underground, where they can do more damage with time. Cry if you feel like it. Notice if you feel relief after the tears stop.
  • If you are feeling sad, plan a sadness day. Plan a day or evening just to be alone, listen to melancholy music, and to observe your thoughts and feelings.
    Planning time to be unhappy can be actually feel good. It can help you ultimately move into a more happy mood.
  • Think about the context of the sad feelings. Are they related to a loss or an unhappy event? It is usually not as simple as discovering the “cause” of the sadness, but it may be possible to understand factors involved.
  • Sadness can result from a change that you did not expect, or it can signal the need for a change in your life. Change is usually stressful, but it is necessary for growth.
  • Know when sadness turns into depression. Get help if this happens rather than getting stuck in it.

Get help if you experience more than a couple of the following symptoms of depression:

  • Persistent sad, anxious, or “empty” mood
  • Feelings of hopelessness, pessimism
  • Feelings of guilt, worthlessness, helplessness
  • Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
  • Decreased energy, fatigue, being “slowed down”
  • Difficulty concentrating, remembering, making decisions
  • Insomnia, early-morning awakening, or oversleeping
  • Appetite and/or weight loss or overeating and weight gain
  • Thoughts of death or suicide; suicide attempts
  • Restlessness, irritability
  • Persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders, and chronic pain.